Evidence map›Paper›PMID 31871888›Full record

ReviewPhotoacoustics2019

A review of clinical photoacoustic imaging: Current and future trends.

Amalina Binte Ebrahim Attia, Ghayathri Balasundaram, Mohesh Moothanchery, U S Dinish, Renzhe Bi, Vasilis Ntziachristos, Malini Olivo

Open access · goldAbstract readReview
In one paragraph

Review in Photoacoustics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 342 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
342citing papers in PubMed, 2 pooled it
34.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

342 citing papers in PubMed, 2 syntheses or guidelines pooled it, 853 citations in OpenAlex.

  1. S1 guideline for imaging diagnostics for skin diseases.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Guideline
  2. Pooled it
  3. Assessment of Breast Tumors Using Multispectral Optoacoustic Tomography in a Surgical Setting.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Trial
  4. Article
  5. Article
  6. Photoacoustic imaging of intestinal physiological biomarkers in infants and children.medRxiv : the preprint server for health sciences · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Volumetric FLASH dosimetryPhysics in medicine and biology · 2026
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

282 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Amalina Binte Ebrahim AttiaLaboratory of Bio-optical Imaging, Singapore Bioimaging Consortium, ASTAR, Singapore.
Ghayathri BalasundaramLaboratory of Bio-optical Imaging, Singapore Bioimaging Consortium, ASTAR, Singapore.
Mohesh MoothancheryLaboratory of Bio-optical Imaging, Singapore Bioimaging Consortium, ASTAR, Singapore.
U S DinishLaboratory of Bio-optical Imaging, Singapore Bioimaging Consortium, ASTAR, Singapore.
Renzhe BiLaboratory of Bio-optical Imaging, Singapore Bioimaging Consortium, ASTAR, Singapore.
Vasilis NtziachristosInstitute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany.
Malini OlivoLaboratory of Bio-optical Imaging, Singapore Bioimaging Consortium, ASTAR, Singapore.
Agency for Science, Technology and Research · SGHelmholtz Zentrum München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoacoustic imaging (or optoacoustic imaging) is an upcoming biomedical imaging modality availing the benefits of optical resolution and acoustic depth of penetration. With its capacity to offer structural, functional, molecular and kinetic information making use of either endogenous contrast agents like hemoglobin, lipid, melanin and water or a variety of exogenous contrast agents or both, PAI has demonstrated promising potential in a wide range of preclinical and clinical applications. This review provides an overview of the rapidly expanding clinical applications of photoacoustic imaging including breast imaging, dermatologic imaging, vascular imaging, carotid artery imaging, musculoskeletal imaging, gastrointestinal imaging and adipose tissue imaging and the future directives utilizing different configurations of photoacoustic imaging. Particular emphasis is placed on investigations performed on human or human specimens.

Indexed as

AR-PAM, acoustic resolution-photoacoustic microscopyClinical applicationsDAQ, data acquisitionFOV, field-of-viewHb, deoxy-hemoglobinHbO2, oxy-hemoglobinLED, light emitting diodeMAP, maximum amplitude projectionMEMS, microelectromechanical systemsMRI, magnetic resonance imagingMSOT, multispectral optoacoustic tomographyOCT, optical coherence tomographyOptoacoustic mesoscopyOptoacoustic tomographyOR-PAM, optical resolution-photoacoustic microscopyPAI, photoacoustic imagingPAM, photoacoustic microscopyPA, photoacousticPAT, photoacoustic tomographyPhotoacoustic imagingPhotoacoustic microscopyRSOM, raster-scanning optoacoustic mesoscopySBH-PACT, single breath hold photoacoustic computed tomography systemsO2, saturationUS, ultrasound

Identifiers

PMID31871888
PMCPMC6911900
OpenAlexW2985896406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.