ArticleEcology and evolution2019
External disturbances impact helminth-host interactions by affecting dynamics of infection, parasite traits, and host immune responses.
Article in Ecology and evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 21 citations in OpenAlex.
- Gastrointestinal helminths increaseeLife · 2022Article
- The potential roles of interleukin-25 in infectious diseases.Frontiers in immunology · 2022Review
- Within-host mechanisms of immune regulation explain the contrasting dynamics of two helminth species in both single and dual infections.PLoS computational biology · 2020Article
- Ecological Factors Mediate Immunity and Parasitic Co-Infection in Sea Fan Octocorals.Frontiers in immunology · 2020Article
- External disturbances impact helminth-host interactions by affecting dynamics of infection, parasite traits, and host immune responses.Ecology and evolution · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
External perturbations, such as multispecies infections or anthelmintic treatments, can alter host-parasite interactions with consequences on the dynamics of infection. While the overall profile of infection might appear fundamentally conserved at the host population level, perturbations can disproportionately affect components of parasite demography or host responses, and ultimately impact parasite fitness and long-term persistence.We took an immuno-epidemiological approach to this reasoning and examined a rabbit-helminth system where animals were trickle-dosed with either one or two helminth species, treated halfway through the experiment with an anthelmintic and reinfected one month later following the same initial regime. Parasite traits (body length and fecundity) and host immune responses (cytokines, transcription factors, antibodies) were quantified at fixed time points and compared before and after drug treatment, and between single and dual infections.Findings indicated a resistant host phenotype to
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.