Evidence map›Paper›PMID 31871556›Full record

ArticleOxidative medicine and cellular longevity2019

Potential Role of Nutrient Intake and Malnutrition as Predictors of Uremic Oxidative Toxicity in Patients with End-Stage Renal Disease.

Robson E Silva, Ana C Simões-E-Silva, Aline S Miranda, Patrícia B I Justino, Maísa R P L Brigagão, Gabriel O I Moraes, Reggiani V Gonçalves, Rômulo D Novaes

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Construction of aRenal failure · 2024
    Article
  2. Oxidative Stress in Non-Dialysis-Dependent Chronic Kidney Disease Patients.International journal of environmental research and public health · 2021
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Robson E SilvaSchool of Medicine, Federal University of Alfenas, Alfenas, 37130-001 Minas Gerais, Brazil.
Ana C Simões-E-SilvaDepartment of Pediatrics, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, 30130-100 Minas Gerais, Brazil.ORCID https://orcid.org/0000-0001-9222-3882
Aline S MirandaDepartment of Morphology, Federal University of Minas Gerais, Belo Horizonte, 31270-910 Minas Gerais, Brazil.ORCID https://orcid.org/0000-0003-2811-7924
Patrícia B I JustinoUniversity Hospital Alzira Velano, Alfenas, 37132-202 Minas Gerais, Brazil.
Maísa R P L BrigagãoInstitute of Biomedical Sciences, Federal University of Alfenas, Alfenas, 37130-001 Minas Gerais, Brazil.
Gabriel O I MoraesInstitute of Biomedical Sciences, Federal University of Alfenas, Alfenas, 37130-001 Minas Gerais, Brazil.
Reggiani V GonçalvesDepartment of Animal Biology, Federal University of Viçosa, Viçosa, 36570-000 Minas Gerais, Brazil.ORCID https://orcid.org/0000-0002-5831-3590
Rômulo D NovaesInstitute of Biomedical Sciences, Federal University of Alfenas, Alfenas, 37130-001 Minas Gerais, Brazil.ORCID https://orcid.org/0000-0002-3186-5328
Universidade Federal de Alfenas · BRUniversidade Federal de Minas Gerais · BRUniversidade Federal de Viçosa · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress is an important risk factor for cardiovascular disease and death in hemodialysis (HD) patients. However, whether biochemical and nutritional markers might be useful to stratify HD patients according to the risk of oxidative damage remains unclear. We investigated whether low-cost and easily available parameters such as the profile of nutrients intake, nutritional status, and antioxidant defenses can predict lipid and protein oxidation in HD patients. Forty-nine HD patients (women = 20, men = 29), ranging from 18 to 65 years of age (73.5%) were submitted to biochemical and nutritional analysis. At least 93.9% of HD patients had malnutrition. A patient's stratification according to nutritional risk was highly coherent with anthropometric parameters and nutrients intake, which were complementarily used as markers of malnutrition. Nutritional stratification was unable to reveal differences in the oxidative status. On the other hand, carbohydrate and zinc intake, serum zinc (Zn), glutathione peroxidase (GPx) activity, total antioxidant capacity (TAC), and nonprotein antioxidants (npAC) in serum were predictive markers of lipid (

Indexed as

AdolescentAdultAgedAntioxidantsBiomarkersCreatinineEnergy IntakeFemaleHemoglobinsHumansKidney Failure, ChronicMaleMiddle AgedNutritional StatusOxidation-ReductionOxidative StressAntioxidantsBiomarkersCreatinineHemoglobinsUreaZinc

Identifiers

PMID31871556
PMCPMC6906803
OpenAlexW2989774063

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.