Evidence map›Paper›PMID 31871549›Full record

ArticleOxidative medicine and cellular longevity2019

Alpha-Synuclein Preserves Mitochondrial Fusion and Function in Neuronal Cells.

Gaia Faustini, Elena Marchesan, Laura Zonta, Federica Bono, Emanuela Bottani, Francesca Longhena, Elena Ziviani, Alessandra Valerio, Arianna Bellucci

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

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  13. Neurons and Glia Interplay in α-Synucleinopathies.International journal of molecular sciences · 2021
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  20. MERCs. The Novel Assistant to Neurotransmission?Frontiers in neuroscience · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Gaia FaustiniDepartment of Molecular and Translational Medicine, University of Brescia, Viale Europa, 11, 25123 Brescia, Italy.ORCID https://orcid.org/0000-0002-0751-3082
Elena MarchesanDepartment of Biology, University of Padova, Via Ugo Bassi, 58b, 35131 Padova, Italy.
Laura ZontaDepartment of Biology, University of Padova, Via Ugo Bassi, 58b, 35131 Padova, Italy.
Federica BonoLaboratory of Preventive and Personalized Medicine, University of Brescia, Viale Europa, 11, 25123 Brescia, Italy.
Emanuela BottaniDepartment of Molecular and Translational Medicine, University of Brescia, Viale Europa, 11, 25123 Brescia, Italy.
Francesca LonghenaDepartment of Molecular and Translational Medicine, University of Brescia, Viale Europa, 11, 25123 Brescia, Italy.ORCID https://orcid.org/0000-0001-6569-9412
Elena ZivianiDepartment of Biology, University of Padova, Via Ugo Bassi, 58b, 35131 Padova, Italy.
Alessandra ValerioDepartment of Molecular and Translational Medicine, University of Brescia, Viale Europa, 11, 25123 Brescia, Italy.
Arianna BellucciDepartment of Molecular and Translational Medicine, University of Brescia, Viale Europa, 11, 25123 Brescia, Italy.ORCID https://orcid.org/0000-0002-9581-1919
University of Brescia · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysregulations of mitochondria with alterations in trafficking and morphology of these organelles have been related to Parkinson's disease (PD), a neurodegenerative disorder characterized by brain accumulation of Lewy bodies (LB), intraneuronal inclusions mainly composed of

Indexed as

alpha-SynucleinAnimalsBlotting, WesternCells, CulturedLewy BodiesMiceMice, Inbred C57BLMicroscopy, Electron, TransmissionMitochondriaMitochondrial DynamicsNeuronsalpha-Synuclein

Identifiers

PMID31871549
PMCPMC6907050
OpenAlexW2989613157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.