Evidence map›Paper›PMID 31871538›Full record

ArticleOxidative medicine and cellular longevity2019

Maternal Smoking Highly Affects the Function, Membrane Integrity, and Rheological Properties in Fetal Red Blood Cells.

Krisztina N Dugmonits, Payal Chakraborty, Réka Hollandi, Szabolcs Zahorán, Gabriella Pankotai-Bodó, Péter Horváth, Hajnalka Orvos, Edit Hermesz

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Special Issue "Targeting Oxidative Stress for Disease: 2nd Edition".International journal of molecular sciences · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Molecular Study on Twin Cohort with Discordant Birth Weight.Antioxidants (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Krisztina N DugmonitsDepartment of Biochemistry and Molecular Biology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Közép fasor 52, Hungary.
Payal ChakrabortyDepartment of Biochemistry and Molecular Biology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Közép fasor 52, Hungary.
Réka HollandiInstitute of Biochemistry, Biological Research Centre, Hungarian Academy of Sciences, Szeged, Hungary.
Szabolcs ZahoránDepartment of Biochemistry and Molecular Biology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Közép fasor 52, Hungary.
Gabriella Pankotai-BodóDepartment of Pathology, Faculty of Medicine, University of Szeged, Szeged, Hungary.
Péter HorváthInstitute of Biochemistry, Biological Research Centre, Hungarian Academy of Sciences, Szeged, Hungary.
Hajnalka OrvosDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Szeged, Szeged, Hungary.
Edit HermeszDepartment of Biochemistry and Molecular Biology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Közép fasor 52, Hungary.ORCID https://orcid.org/0000-0002-0543-6693
University of Szeged · HUHUN-REN Szegedi Biológiai Kutatóközpont · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An understanding of the basic pathophysiological mechanisms of neonatal diseases necessitates detailed knowledge about the wide range of complications in the circulating fetal RBCs. Recent publications on adult red blood cells (RBCs) provide evidence that RBCs carry an active nitric oxide synthase (NOS3) enzyme and contribute to vascular functioning and integrity via their active nitric oxide synthesis. The aim of this study was to determine the effect of maternal smoking on the phenotypical appearance and functionality of fetal RBCs, based on morphological and molecular studies. We looked for possible links between vascular dysfunction and NOS3 expression and activation and its regulation by arginase (ARG1). Significant morphological and functional differences were found between fetal RBCs isolated from the arterial cord blood of neonates born to nonsmoking (RBC-NS,

Indexed as

AcetatesArginaseCadmiumCandidaCells, CulturedErythrocytesFemaleFetal BloodHumansMaternal ExposureNitric Oxide Synthase Type IIIPeroxynitrous AcidPhosphorylationPregnancySmokingAcetatesArginaseCadmiumcadmium acetateNitric Oxide Synthase Type IIINOS3 protein, humanPeroxynitrous Acid

Identifiers

PMID31871538
PMCPMC6906794
OpenAlexW2991209439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.