ArticleCentral-European journal of immunology2019
Analysis of the level of selected parameters of inflammation, circulating immune complexes, and related indicators (neutrophil/lymphocyte, platelet/lymphocyte, CRP/CIC) in patients with obstructive diseases.
Article in Central-European journal of immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Role of platelet-to-lymphocyte count ratio (PLR), as a prognostic indicator in COVID-19: A systematic review and meta-analysis.Journal of medical virology · 2022Pooled it
- Associations Between Complete Blood Count-Derived Inflammation Indices and Emergence Delirium in Children Undergoing Adenotonsillectomy.Paediatric anaesthesia · 2026Article
- Association between platelet-to-neutrophil ratio and asthma-COPD overlap: a cross-sectional study in China.Frontiers in medicine · 2026Article
- Immune cell regulatory networks in chronic obstructive pulmonary disease: mechanistic analysis from innate to adaptive immunity.Frontiers in immunology · 2025Review
- Association Between Systemic Immune-Inflammation Index and Psoriasis, Psoriasis Comorbidities, and All-Cause Mortality: A Study Based on NHANES.Immunity, inflammation and disease · 2024Review
- Elevated Neutrophil-to-Lymphocyte Ratio Is Associated with Severe Asthma Exacerbation in Children.Journal of clinical medicine · 2023Article
- Hematological Parameters as Diagnostic Factors: Correlation with Severity of COVID-19.Acta bio-medica : Atenei Parmensis · 2022Article
- Article
- C-Reactive Protein-to-Albumin Ratio as a Prognostic Inflammatory Marker in COVID-19.Journal of laboratory physicians · 2022Article
- Clinical characteristics and mortality predictors of patients with cancer hospitalized by COVID-19 in a pediatric third-level referral center.Frontiers in pediatrics · 2022Article
- The demographic characteristics, prognosis, and relationship with cancer subtypes of hospitalized COVID-19 patients with malignancy: A single-center experience.Journal of medical virology · 2021Article
- The Dynamics of Circulating Immune Complexes in Horses with Severe Equine Asthma.Animals : an open access journal from MDPI · 2021Article
- Commonalities Between COVID-19 and Radiation Injury.Radiation research · 2021Review
- Platelet-to-lymphocyte ratio is associated with prognosis in patients with coronavirus disease-19.Journal of medical virology · 2020Article
- A novel indicator predicts 2019 novel coronavirus infection in subjects with diabetes.Diabetes research and clinical practice · 2020Article
- Targeting Neprilysin (NEP) pathways: A potential new hope to defeat COVID-19 ghost.Biochemical pharmacology · 2020Review
- The Value of Inflammatory Biomarkers in Differentiating Asthma-COPD Overlap from COPD.International journal of chronic obstructive pulmonary disease · 2020Article
- Effect of blood analysis and immune function on the prognosis of patients with COVID-19.PloS one · 2020Article
- Systemic Immune-Inflammation Index (SII) Predicts Increased Severity in Psoriasis and Psoriatic Arthritis.Current health sciences journalArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionChronic obstructive pulmonary disease (COPD) is an inflammatory disorder of the airways. An important element of COPD assessment is the evaluation of immune mechanisms involved in non-specific and specific response to ongoing inflammation. AIM OF THE STUDY: To evaluate the level of selected inflammatory and immunological parameters in patients with COPD, including C-reactive protein (CRP) and circulating immune complexes (CIC), as well as CRP/CIC index. MATERIAL AND
methodsThe study group consisted of 49 patients with obstructive pulmonary diseases (COPD, asthma, and asthma-COPD overlap syndrome) hospitalised in the Department of Pulmonary Diseases, Kuyavian-Pomeranian Pulmonology Centre in Bydgoszcz. Patients with COPD were divided into two subgroups, taking into account the severity of the disease according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD; stages B and D). The control group consisted of 30 healthy persons. Levels of CIC were determined by the method of Hasková, and the concentration of CRP in serum by the standard immunoturbidimetric method.
resultsThe median values of examined parameters (neutrophils, lymphocytes, platelets, neutrophil/lymphocyte ratio - NLR, platelet/lymphocyte ratio - PLR, CRP, CIC, and CRP/CIC index) were significantly higher among patients with obstructive diseases than in the control group. A tendency towards higher lymphocyte count, CRP, and CRP/CIC index in COPD stage D, compared to stage B, was observed.
conclusionsBased on our results, we suggest that the role of non-specific inflammatory mechanisms may increase in more advanced COPD stages (D), compared to less advanced stages (B).
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