Evidence map›Paper›PMID 31871231›Full record

ReviewCold Spring Harbor perspectives in medicine2020

Connecting Genotype with Behavioral Phenotype in Mouse Models of Autism Associated with

Amy E Clipperton-Allen, Damon T Page

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Altered Primary Somatosensory Neuron Development in a Pten Heterozygous Model for Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. iScience · 2022
    Article
  6. Review
  7. Article
  8. Autism Spectrum Disorder Associated with Germline HeterozygousCold Spring Harbor perspectives in medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Amy E Clipperton-AllenDepartment of Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Damon T PageDepartment of Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Scripps Research Institute · US

Funding

Regulation of mTOR signaling in the developing cerebral cortex as a point of convergence for multiple autism risk factorsR01MH108519 · NIMH · UNIVERSITY OF FLORIDA · PI PAGE, DAMON THERON · 2016 to 2025
$4.8M
Impact of Pten mutations on brain growth and social behavioral development.R01MH105610 · NIMH · SCRIPPS FLORIDA · PI PAGE, DAMON THERON · 2015 to 2019
$2.4M
NIMH NIH HHS R01 MH105610NIMH NIH HHS R01 MH108519
6 · The paper itself

Abstract

A subset of individuals with autism spectrum disorder (ASD) and macrocephaly carry mutations in the gene

Indexed as

BehaviorAnimalsAutism Spectrum DisorderDisease Models, AnimalGenotypeHumansMegalencephalyMiceMutationPhenotypePTEN PhosphohydrolasePTEN PhosphohydrolasePTEN protein, human

Identifiers

PMID31871231
PMCPMC7461765
OpenAlexW2998177660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.