Evidence map›Paper›PMID 31871102›Full record

ArticleInfection and immunity2020

The Cryptic Plasmid Improves

Jingyue Ma, Conghui He, Zhi Huo, Ying Xu, Bernard Arulanandam, Quanzhong Liu, Guangming Zhong

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Frontiers in cellular and infection microbiology · 2025
    Article
  2. Article
  3. Plasmid-mediated virulence inFrontiers in cellular and infection microbiology · 2023
    Review
  4. Article
  5. Review
  6. Gastrointestinal Chlamydia-Induced CD8Infection and immunity · 2021
    Article
  7. Article
  8. Robust Heat Shock Response inFrontiers in microbiology · 2021
    Article
  9. Infection and immunity · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jingyue Ma *Department of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Conghui He *Department of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Zhi HuoDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Ying XuDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Bernard ArulanandamDepartment of Biology, University of Texas at San Antonio, San Antonio, Texas, USA.
Quanzhong LiuDepartment of Dermatovenereology, Tianjin Medical University General Hospital, Tianjin, China.
Guangming ZhongDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA Zhongg@uthscsa.edu.
The University of Texas Health Science Center at San Antonio · USThe University of Texas at San Antonio · USTianjin Medical University General Hospital · CN

Funding

MECHANISMS OF CHLAMYDIAL EVASION OF IMMUNE RECOGNATIONR01AI047997 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ZHONG, GUANGMING · 2000 to 2021
$6.9M
Chlamydial plasmid-dependent pathogenesisR01AI121989 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ZHONG, GUANGMING · 2016 to 2019
$1.9M
NIAID NIH HHS R01 AI047997NIAID NIH HHS R01 AI121989
6 · The paper itself

Abstract

The cryptic plasmid is important for chlamydial colonization in the gastrointestinal tract. We used a combination of intragastric, intrajejunal, and intracolon inoculations to reveal the impact of the plasmid on chlamydial colonization in distinct regions of gastrointestinal tract. Following an intragastric inoculation, the plasmid significantly improved chlamydial colonization. At the tissue level, plasmid-positive

Indexed as

AnimalsChlamydia InfectionsChlamydia muridarumColony Count, MicrobialFemaleGastrointestinal TractGenome, BacterialHost-Pathogen InteractionsMiceMice, Inbred C57BLOrgan SpecificityPlasmidsChlamydiaChlamydia muridarumgastrointestinal tractGI tract colonizationpersistenceplasmid

Identifiers

PMID31871102
PMCPMC7035928
OpenAlexW2997211084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.