Evidence map›Paper›PMID 31871100›Full record

ArticleInfection and immunity2020

Redundant and Cooperative Roles for Yersinia pestis Yop Effectors in the Inhibition of Human Neutrophil Exocytic Responses Revealed by Gain-of-Function Approach.

Amanda R Pulsifer, Aruna Vashishta, Shane A Reeves, Jennifer K Wolfe, Samantha G Palace, Megan K Proulx, Jon Goguen, Sobha R Bodduluri, Bodduluri Haribabu, Silvia M Uriarte and 1 more

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
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  4. Distinct Mechanisms of Type 3 Secretion System Recognition Control LTBbioRxiv : the preprint server for biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Amanda R PulsiferDepartment of Microbiology and Immunology, University of Louisville School of Medicine, Louisville, Kentucky, USA.ORCID 0000-0002-0661-819X
Aruna VashishtaDepartment of Medicine, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Shane A ReevesDepartment of Microbiology and Immunology, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Jennifer K WolfeCenter for Predictive Medicine for Biodefense and Emerging Infectious Diseases, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Samantha G PalaceDepartment of Microbiology and Physiology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID 0000-0002-7849-8078
Megan K ProulxDepartment of Microbiology and Physiology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID 0000-0002-9524-8302
Jon GoguenDepartment of Microbiology and Physiology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID 0000-0002-1372-1697
Sobha R BodduluriDepartment of Microbiology and Immunology, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Bodduluri HaribabuDepartment of Microbiology and Immunology, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Silvia M UriarteDepartment of Medicine, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Matthew B LawrenzDepartment of Microbiology and Immunology, University of Louisville School of Medicine, Louisville, Kentucky, USA matt.lawrenz@louisville.edu.ORCID 0000-0003-1505-5429
University of Louisville · USUniversity of Massachusetts Chan Medical School · US

Funding

Understanding the Host-Microbiome-Therapeutic Triad: Implications for Designing Alternative IntravaginalP20GM125504 · NIGMS · UNIVERSITY OF LOUISVILLE · PI Shirin Ghods · 2018 to 2026
$24.4M
Innate Immunity Training ProgramT32AI095213 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SILVERMAN, NEAL · 2011 to 2025
$2.5M
Elucidating the Biogenesis of the Yersinia pestis Containing VacuoleR21AI119557 · NIAID · UNIVERSITY OF LOUISVILLE · PI LAWRENZ, MATTHEW B · 2016 to 2017
$413k
NIAID NIH HHS R21 AI119557NIAID NIH HHS T32 AI095213NIGMS NIH HHS P20 GM125504
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ProteinsCell DegranulationGain of Function MutationHost-Pathogen InteractionsHumansLeukotriene B4NeutrophilsPlagueSecretory VesiclesType III Secretion SystemsVirulence FactorsYersinia pestisBacterial ProteinsLeukotriene B4Type III Secretion SystemsVirulence Factorsgranules and degranulationleukotrieneneutrophilsplaguetype 3 secretionYersinia pestis

Identifiers

PMID31871100
PMCPMC7035916
OpenAlexW2996849603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.