Evidence map›Paper›PMID 31871033›Full record

ArticleJournal of bacteriology2020

A Screen for Antibiotic Resistance Determinants Reveals a Fitness Cost of the Flagellum in Pseudomonas aeruginosa.

E A Rundell, N Commodore, A L Goodman, B I Kazmierczak

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Vancomycin Sensitization inACS infectious diseases · 2025
    Article
  5. Review
  6. Review
  7. Exposure ofAntibiotics (Basel, Switzerland) · 2022
    Article
  8. Frontiers in microbiology · 2022
    Review
  9. Flagella, Chemotaxis and Surface Sensing.Advances in experimental medicine and biology · 2022
    Article
  10. Article
  11. Motility increase of adherent invasiveFrontiers in microbiology · 2022
    Article
  12. High-throughput discovery of phage receptors using transposon insertion sequencing of bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

E A RundellProgram in Microbiology, Yale School of Medicine, New Haven, Connecticut, USA.
N CommodoreDepartment of Medicine (Infectious Diseases), Yale School of Medicine, New Haven, Connecticut, USA.
A L GoodmanMicrobial Sciences Institute, Department of Microbial Pathogenesis, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-7599-3471
B I KazmierczakDepartment of Medicine (Infectious Diseases), Yale School of Medicine, New Haven, Connecticut, USA barbara.kazmierczak@yale.edu.ORCID 0000-0002-8162-803X
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
PREDOCTORAL TRAINING PROGRAM IN MICROBIAL PATHOGENESIST32AI007640 · NIAID · YALE UNIVERSITY · PI GOODMAN, ANDREW L · 2000 to 2022
$4.3M
Targeting intrinsic resistance to combat multi-drug resistant P. aeruginosaR21AI123984 · NIAID · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 2016 to 2017
$446k
Using intrabodies to identify determinants of intrinsic antibiotic resistance in Pseudomonas aeruginosaF31AI131531 · NIAID · YALE UNIVERSITY · PI RUNDELL, ETHAN · 2018 to 2019
$59k
NCATS NIH HHS UL1 TR001863NIAID NIH HHS F31 AI131531NIAID NIH HHS R21 AI123984NIAID NIH HHS T32 AI007640
6 · The paper itself

Abstract

The intrinsic resistance of

Indexed as

Drug Resistance, BacterialFlagellaGenetic FitnessAnti-Bacterial AgentsBacterial Outer Membrane ProteinsBiological TransportDose-Response Relationship, DrugGene Expression Regulation, BacterialHumansPseudomonas aeruginosaQuorum SensingAnti-Bacterial AgentsBacterial Outer Membrane ProteinseffluxflagellumINSeqintrinsic resistanceouter membranePseudomonas aeruginosaquorum sensing

Identifiers

PMID31871033
PMCPMC7043666
OpenAlexW2996953746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.