Evidence map›Paper›PMID 31870321›Full record

Observational studyBMC nephrology2019

The SURF (Italian observational study for renal insufficiency evaluation in liver transplant recipients): a post-hoc between-sex analysis.

Delia Colombo, Alessandro Zullo, Lucia Simoni, Emanuela Zagni, SURF Study Group

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Delia ColomboNovartis Farma S.p.A, Largo Umberto Boccioni, 21040, Origgio, VA, Italy.
Alessandro ZulloMediNeos Observational Research, Modena, Italy.
Lucia SimoniMediNeos Observational Research, Modena, Italy.
Emanuela ZagniNovartis Farma S.p.A, Largo Umberto Boccioni, 21040, Origgio, VA, Italy. emanuela.zagni@novartis.com.ORCID 0000-0003-2772-9769
SURF Study Group
Novartis (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFemale sex has been reported as an independent predictor of severe post-liver transplantation (LT) chronic kidney disease. We performed a by sex post-hoc analysis of the SURF study, that investigated the prevalence of renal impairment following LT, aimed at exploring possible differences between sexes in the prevalence and course of post-LT renal damage.

methodsAll patients enrolled in the SURF study were considered evaluable for this sex-based analysis, whose primary objective was to evaluate by sex the proportion of patients with estimated Glomerular Filtration Rate (eGFR) < 60 ml/min/1.73m

resultsSeven hundred thirty-eight patients were included in our analysis, 76% males. The proportion of patients with eGFR < 60 mL/min/1.73 m

conclusionsThough the limitation of being performed post-hoc, this analysis suggests potential sex differences in the prevalence of renal impairment before and after LT, encouraging further clinical research to explore such differences more in depth.

Indexed as

Sex CharacteristicsTransplant RecipientsAdultAgedCross-Sectional StudiesFemaleFollow-Up StudiesGlomerular Filtration RateHumansItalyLiver TransplantationLongitudinal StudiesMaleMiddle AgedRenal InsufficiencyRetrospective StudiesCalcineurin inhibitorsGenderLiver transplantMeta-analysisRenal insufficiencySex differences

Identifiers

PMID31870321
PMCPMC6929500
OpenAlexW2994859573

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.