ArticleBMC genomics2019
Genomic dissection of the most prevalent Listeria monocytogenes clone, sequence type ST87, in China.
Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 38 citations in OpenAlex.
- Persisting predominant clinical CC87Emerging microbes & infections · 2026Review
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- Maternal-Fetal Listeriosis in China: Clinical and Genomic Characteristics From an ST8Infection and drug resistance · 2025Article
- Prevalence and characteristics ofFrontiers in microbiology · 2025Article
- Virulence Gene Profiling and Molecular Typing of Clinical Isolates ofInfection and drug resistance · 2025Article
- EⅡB Mutation Reduces the Pathogenicity ofVeterinary sciences · 2024Article
- Clinical and Bacterial Characteristics of Bloodstream Infections Caused byThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024Article
- Clinical and Genomic Characteristics of a Clinical Listeria Monocytogenes ST120 Isolate Recovered from a Pregnant Woman.Infection and drug resistance · 2024Article
- Current methodologies available to evaluate the virulence potential amongFrontiers in microbiology · 2024Review
- The Isolation, Genetic Analysis and Biofilm Characteristics ofMicroorganisms · 2023Article
- Maternal bacteremia caused byHeliyon · 2023Article
- Large-scale genetic analysis and biological traits of two SigB factors inFrontiers in microbiology · 2023Article
- Genomic and pathogenicity islands ofFrontiers in molecular biosciences · 2023Review
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- Dissecting Listeria monocytogenes Persistent Contamination in a Retail Market Using Whole-Genome Sequencing.Microbiology spectrum · 2022Article
- Whole-genome sequencing reveals genomic characterization ofFrontiers in microbiology · 2022Article
- The population structure and genetic diversity ofFrontiers in microbiology · 2022Article
- Prevalence and Genetic Diversity ofFrontiers in microbiology · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundListeria monocytogenes consists of four lineages that occupy a wide variety of ecological niches. Sequence type (ST) 87 (serotype 1/2b), belonging to lineage I, is one of the most common STs isolated from food products, food associated environments and sporadic listeriosis in China. Here, we performed a comparative genomic analysis of the L. monocytogenes ST87 clone by sequencing 71 strains representing a diverse range of sources, different geographical locations and isolation years.
resultsThe core genome and pan genome of ST87 contained 2667 genes and 3687 genes respectively. Phylogenetic analysis based on core genome SNPs divided the 71 strains into 10 clades. The clinical strains were distributed among multiple clades. Four clades contained strains from multiple geographic regions and showed high genetic diversity. The major gene content variation of ST87 genomes was due to putative prophages, with eleven hotspots of the genome that harbor prophages. All strains carry an intact CRISRP/Cas system. Two major CRISPR spacer profiles were found which were not clustered phylogenetically. A large plasmid of about 90 Kb, which carried heavy metal resistance genes, was found in 32.4% (23/71) of the strains. All ST87 strains harbored the Listeria pathogenicity island (LIPI)-4 and a unique 10-open read frame (ORF) genomic island containing a novel restriction-modification system.
conclusionWhole genome sequence analysis of L. monocytogenes ST87 enabled a clearer understanding of the population structure and the evolutionary history of ST87 L. monocytogenes in China. The novel genetic elements identified may contribute to its virulence and adaptation to different environmental niches. Our findings will be useful for the development of effective strategies for the prevention and treatment of listeriosis caused by this prevalent clone.
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