Evidence map›Paper›PMID 31870279›Full record

ReviewThe journal of headache and pain2019

Mechanisms of migraine as a chronic evolutive condition.

Anna P Andreou, Lars Edvinsson

3 registry-linked trialsOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The journal of headache and pain, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 137 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 7 pooled it
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06109389 phase2unknown statusnot on this mapstarted 2023, after this paper: background citation

The Efficacy of Intravenous Lidocaine Infusion in Chronic Unilateral Migraine Headache Clinical and Laboratory Assessment .Aprospective Randomized Double Blind Controlled Study

TypeinterventionalSponsorAlexandria UniversityRan2023 to 2024Enrolled80ConditionsChronic Migraine, HeadacheArmsLidocaine IV
NCT06212869 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Green Light and Transcranial Direct Current Stimulation in Migraine Patients; a Randomized Control Trial.

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2024Enrolled45ConditionsMigraineArmsTranscranial direct current stimulation, Sham transcranial direct current stimulation, Green light
NCT06504537 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Comparative Effects of Theragun Percussion Therapy and Compression Therapy on Pain, Neck Range of Motion and Quality of Life in The Patients With Migraine

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2024Enrolled50ConditionsMigraineArmsTHERAGUN PERCUSSION THERAPY, COMPRESSION THERAPY
3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 7 syntheses or guidelines pooled it, 284 citations in OpenAlex.

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  12. HIT-6 and EQ-5D-5L in patients with migraine: assessment of common latent constructs and development of a mapping algorithm.The European journal of health economics : HEPAC : health economics in prevention and care · 2022
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77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Anna P AndreouHeadache Research, Wolfson CARD, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. anna.andreou@headache-research.com.ORCID http://orcid.org/0000-0002-7008-6626
Lars EdvinssonDepartment of Medicine, Lund University, 22185, Lund, Sweden.
King's College London · GBLund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the mechanisms of migraine remains challenging as migraine is not a static disorder, and even in its episodic form migraine remains an "evolutive" chronic condition. Considerable progress has been made in elucidating the pathophysiological mechanisms of migraine, associated genetic factors that may influence susceptibility to the disease, and functional and anatomical changes during the progression of a migraine attack or the transformation of episodic to chronic migraine. Migraine is a life span neurological disorder that follows an evolutive age-dependent change in its prevalence and even clinical presentations. As a disorder, migraine involves recurrent intense head pain and associated unpleasant symptoms. Migraine attacks evolve over different phases with specific neural mechanisms and symptoms being involved during each phase. In some patients, migraine can be transformed into a chronic form with daily or almost daily headaches. The mechanisms behind this evolutive process remain unknown, but genetic and epigenetic factors, inflammatory processes and central sensitization may play an important role.

Indexed as

Central Nervous System SensitizationChronic DiseaseDisease ProgressionFemaleHeadacheHumansMaleMigraine DisordersPrevalence

Identifiers

PMID31870279
PMCPMC6929435
OpenAlexW2996149780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.