Evidence map›Paper›PMID 31869843›Full record

ReviewSeminars in reproductive medicine2019

Should We Make More Bone or Not, As Told by Kisspeptin Neurons in the Arcuate Nucleus.

Candice B Herber, Holly A Ingraham

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in reproductive medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Candice B HerberDepartment of Cellular and Molecular Pharmacology, School of Medicine, Mission Bay Campus, University of California San Francisco, San Francisco, California.
Holly A IngrahamDepartment of Cellular and Molecular Pharmacology, School of Medicine, Mission Bay Campus, University of California San Francisco, San Francisco, California.
University of California, San Francisco · US

Funding

Dissecting a hormone-responsive processor for female activity and repetitive behaviorR01DK121657 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI INGRAHAM, HOLLY A. · 2020 to 2024
$2.9M
Arcuate ERa Signaling in Central Control of Female Bone MetabolismR01AG062331 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI INGRAHAM, HOLLY A. · 2019 to 2023
$2.3M
NIA NIH HHS R01 AG062331NIDDK NIH HHS R01 DK121657
6 · The paper itself

Abstract

Since its initial discovery in 2002, the neuropeptide Kisspeptin (Kiss1) has been anointed as the master regulator controlling the onset of puberty in males and females. Over the last several years, multiple groups found that Kiss1 signaling is mediated by the 7TM surface receptor GPCR54.

Indexed as

AnimalsArcuate Nucleus of HypothalamusBone DensityBone DevelopmentEstradiolGene Expression RegulationHumansKisspeptinsNeuronsReceptors, EstrogenSex CharacteristicsSignal TransductionEstradiolKisspeptinsReceptors, Estrogen

Identifiers

PMID31869843
PMCPMC7233264
OpenAlexW2997756097

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.