Evidence map›Paper›PMID 31869381›Full record

ArticlePloS one2019

Health literacy as a mediator of the relationship between socioeconomic status and health: A cross-sectional study in a population-based sample in Florence.

Vieri Lastrucci, Chiara Lorini, Saverio Caini, Florence Health Literacy Research Group, Guglielmo Bonaccorsi

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 2 pooled it
16.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 2 syntheses or guidelines pooled it, 185 citations in OpenAlex.

  1. Interventions Addressing Health Literacy in Cancer Care: A Systematic Review of Reviews.International journal of environmental research and public health · 2025
    Pooled it
  2. Employment Status and Alcohol-Attributable Mortality Risk-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  3. Comprehension of an artificial intelligence-generated discharge letter versus a traditional discharge letter: two controlled quasi-experimental parallel-group studies.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2026
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42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Vieri LastrucciDepartment of Health Science, University of Florence, Florence, Italy.ORCID 0000-0003-0762-6666
Chiara LoriniDepartment of Health Science, University of Florence, Florence, Italy.
Saverio CainiCancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy.
Florence Health Literacy Research Group
Guglielmo BonaccorsiDepartment of Health Science, University of Florence, Florence, Italy.
University of Florence · ITPiedmont Reference Center for Epidemiology and Cancer Prevention · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealth literacy(HL) has recently been proposed as a potential mediator in the pathway through which socio-economic status(SES) affects health. However, empirical research investigating the contribution of HL in this relationship remains scarce. This study investigated whether functional HL mediates the association between SES and self-reported health(SRH) in an adult population-based sample.

methodsThe study adopted a cross-sectional design. Education level and financial status were used as measures of SES, while functional HL was assessed with the Newest Vital Sign. Moderated mediation analyses were conducted using SES variables as independent variables, SRH as dependent variable and functional HL as mediator variable. Furthermore, age, sex and chronic diseases were tested as moderators of the effect mediated by functional HL.

results452 subjects completed the study (58,8% female; mean age 53,25±11,7). Results showed that functional HL mediates on average 18.5% of the association between education and SRH (p = 0.02) and 12.9% (p = 0.01) of the association between financial status and SRH. Furthermore, the proportion of effect mediated by functional HL was found to be higher in lower socio-economic classes for both SES variables considered. No significant moderation effects of age, sex or chronic diseases were observed for both SES variables.

conclusionFindings suggest that functional HL may serve as a pathway by which SES affects health status, especially in lower SES groups. HL may be a valuable and actionable intermediate target for addressing health inequalities. However, further studies are needed to better define the mediating role of HL across socio-economic classes.

Indexed as

Health LiteracySocial ClassAdultCross-Sectional StudiesEconomic StatusEducational StatusFemaleHealth StatusHealth Status DisparitiesHumansItalyMaleMiddle AgedPoverty

Identifiers

PMID31869381
PMCPMC6927637
OpenAlexW2995393135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.