Evidence map›Paper›PMID 31869002›Full record

ArticleObesity (Silver Spring, Md.)2020

The Societal Value of Broader Access to Antiobesity Medications.

Mina Kabiri, Alison Sexton Ward, Abhilasha Ramasamy, Emma van Eijndhoven, Rahul Ganguly, B Gabriel Smolarz, Tracy Zvenyach, Dana P Goldman, James R Baumgardner

Open access · bronzeAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Breaking down silos: the multifaceted nature of obesity and the future of weight management.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  6. The Relative Value of Anti-Obesity Medications Compared to Similar Therapies.ClinicoEconomics and outcomes research : CEOR · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Economic value of nonsurgical weight loss in adults with obesity.Journal of managed care & specialty pharmacy · 2021
    Article
  11. Simulating the Fiscal Impact of Anti-Obesity Medications as an Obesity Reduction Strategy.Inquiry : a journal of medical care organization, provision and financing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mina KabiriPrecision Health Economics, Los Angeles, California, USA.ORCID 0000-0002-3486-7652
Alison Sexton WardPrecision Health Economics, Los Angeles, California, USA.
Abhilasha RamasamyNovo Nordisk Inc., Plainsboro, New Jersey, USA.
Emma van EijndhovenPrecision Health Economics, Los Angeles, California, USA.
Rahul GangulyNovo Nordisk Inc., Plainsboro, New Jersey, USA.
B Gabriel SmolarzNovo Nordisk Inc., Plainsboro, New Jersey, USA.ORCID 0000-0002-8591-3858
Tracy ZvenyachNovo Nordisk Inc., Plainsboro, New Jersey, USA.
Dana P GoldmanPrecision Health Economics, Los Angeles, California, USA.ORCID 0000-0001-8498-6396
James R BaumgardnerPrecision Health Economics, Los Angeles, California, USA.
Novo Nordisk (United States) · US

Funding

Novo Nordisk Inc. N/A
6 · The paper itself

Abstract

objectiveObesity and its complications place an enormous burden on society. Yet antiobesity medications (AOM) are prescribed to only 2% of the eligible population, even though few individuals can sustain weight loss using other strategies alone. This study estimated the societal value of greater access to AOM.

methodsBy using a well-established simulation model (The Health Economics Medical Innovation Simulation), the societal value of AOM for the cohort of Americans aged ≥ 25 years in 2019 was quantified. Four scenarios with differential uptake among the eligible population (15% and 30%) were modeled, with efficacy from current and next-generation AOM. Societal value was measured as monetized quality of life, productivity gains, and savings in medical spending, subtracting the costs of AOM.

resultsFor the 217 million Americans aged ≥ 25 years, AOM generated $1.2 trillion in lifetime societal value under a conservative scenario (15% annual uptake using currently available AOM). The introduction of next-generation AOM increased societal value to $1.9 to $2.5 trillion, depending on uptake. Finally, societal value was higher for younger individuals and Black and Hispanic individuals compared with White individuals.

conclusionsThis study suggests that AOM provide substantial gains to patients and society. Policies promoting broader clinical access to and use of AOM warrant consideration to reach national goals to reduce obesity.

Indexed as

Health Services AccessibilitySocial ChangeAdultAgedAged, 80 and overAnti-Obesity AgentsCohort StudiesCost SavingsEthnicityFemaleHumansMaleMiddle AgedObesityQuality of LifeSickness Impact ProfileAnti-Obesity Agents

Identifiers

PMID31869002
PMCPMC7003734
OpenAlexW2995759968

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.