Evidence map›Paper›PMID 31868701›Full record

ArticleJournal of vestibular research : equilibrium & orientation

Estimating loss of canal function in the video head impulse test (vHIT).

Kamran Barin

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Article in Journal of vestibular research : equilibrium & orientation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

1 author.

Kamran BarinDepartment of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe vestibulo-ocular reflex (VOR) gain is the primary parameter for quantifying and interpreting the video head impulse test (vHIT). Yet, the relationship between the VOR gain and the extent of canal function is not clear.

objectiveThe goal of this paper was to determine if the loss of canal function in vHIT can be estimated from the VOR gain.

methodsA model of the VOR was developed that included linear components for the cupula and the velocity storage mechanism as well as nonlinear components for the vestibular nerve and the vestibular nuclei. Multiple simulations were carried out as the level of function for the right and left VOR pathways was varied systematically over their entire range.

resultsSimulation results were similar to the typical findings in normal individuals as well as in patients with unilateral and bilateral loss of canal function. Based on these simulations, a relationship between the canal function and the VOR gains was established. This relationship was surprisingly independent of most model parameters.

conclusionsThe sum of right and left VOR gains (or 2 times the mean of VOR gains) at a given head velocity is an estimate of the total function of the involved canals. This simple formula can estimate the loss of canal function in purely unilateral lesions. For bilateral lesions, the same formula can estimate the total loss of bilateral function but contributions from individual canals cannot be determined without additional information.

Indexed as

Head Impulse TestModels, NeurologicalHumansReflex, Vestibulo-OcularSemicircular CanalsHead impulse testvestibular lossvestibulo-ocular reflex (VOR)VOR Gain

Identifiers

PMID31868701
PMCPMC9249275

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.