Evidence map›Paper›PMID 31868592›Full record

ArticleeLife2019

Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling.

Alec K Gramann, Arvind M Venkatesan, Melissa Guerin, Craig J Ceol

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Agouti and BMP signaling drive a naturally occurring fate conversion of melanophores to leucophores in zebrafish.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. BMP signaling in cancer stemness and differentiation.Cell regeneration (London, England) · 2023
    Review
  10. Review
  11. Article
  12. Bone Morphogenic Protein Signaling and Melanoma.Current treatment options in oncology · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alec K GramannProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, United States.ORCID 0000-0001-7527-5533
Arvind M VenkatesanProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, United States.
Melissa GuerinProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, United States.
Craig J CeolProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, United States.ORCID 0000-0002-7188-7580
University of Massachusetts Chan Medical School · US

Funding

University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
Use of comparative genomics to identify novel regulators of melanoma progressionR01AR063850 · NIAMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI CEOL, CRAIG JOSEPH · 2013 to 2017
$1.8M
Targeting BMP signaling to treat advanced melanoma and suppress therapeutic resistanceF31CA239478 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GRAMANN, ALEC KRAGIE · 2019 to 2020
$45k
Congressionally Directed Medical Research Programs W8IXWH-13-0107NCATS NIH HHS UL1 TR001453NCATS NIH HHS UL1-TR001453NCI NIH HHS 1F31CA239478-01NCI NIH HHS F31 CA239478NIAMS NIH HHS R01 AR063850NIAMS NIH HHS R01AR063850Sidney Kimmel Foundation for Cancer Research SKF-13-123
6 · The paper itself

Abstract

Preventing terminal differentiation is important in the development and progression of many cancers including melanoma. Recent identification of the BMP ligand

Indexed as

AnimalsBone Morphogenetic ProteinsCell DifferentiationGene Expression Regulation, DevelopmentalGrowth Differentiation Factor 6HumansLigandsMelanocytesMicrophthalmia-Associated Transcription FactorNeoplasmsNeural CrestPigmentationSignal TransductionZebrafishZebrafish ProteinsBone Morphogenetic Proteinsgdf6a protein, zebrafishGrowth Differentiation Factor 6LigandsMicrophthalmia-Associated Transcription Factormitfa protein, zebrafishZebrafish Proteinsbmp signalingcancer biologydevelopmental biologymelanocytemelanomamitfneural crestzebrafish

Identifiers

PMID31868592
PMCPMC6968919
OpenAlexW2996552501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.