Evidence map›Paper›PMID 31868588›Full record

ArticleeLife2019

Relaxation of synaptic inhibitory events as a compensatory mechanism in fetal SOD spinal motor networks.

Pascal Branchereau, Elodie Martin, Anne-Emilie Allain, William Cazenave, Laura Supiot, Fara Hodeib, Amandine Laupénie, Urvashi Dalvi, Hongmei Zhu, Daniel Cattaert

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. An impaired splicing program underlies differentiation defects in hSOD1Cellular and molecular life sciences : CMLS · 2023
    Article
  9. Article
  10. Article
  11. Rate-dependent depression is impaired in amyotrophic lateral sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  12. Chloride Homeostasis in Developing Motoneurons.Advances in neurobiology · 2022
    Article
  13. Motoneuron Diseases.Advances in neurobiology · 2022
    Article
  14. Article
  15. Motoneuronal Spinal Circuits in Degenerative Motoneuron Disease.Frontiers in molecular neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pascal BranchereauUniversity of Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.ORCID https://orcid.org/0000-0003-3972-8229
Elodie MartinUniversity of Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.
Anne-Emilie AllainUniversity of Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.
William CazenaveUniversity of Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.
Laura SupiotUniversity of Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.
Fara HodeibUniversity of Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.
Amandine LaupénieUniversity of Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.
Urvashi DalviUniversity of Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.
Hongmei ZhuUniversity of Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.
Daniel CattaertUniversity of Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting motor neurons (MNs) during late adulthood. Here, with the aim of identifying early changes underpinning ALS neurodegeneration, we analyzed the GABAergic/glycinergic inputs to E17.5 fetal MNs from SOD1

Indexed as

Amyotrophic Lateral SclerosisAnimalsChloridesDisease Models, AnimalFetusGABAergic Neuronsgamma-Aminobutyric AcidGlycineHumansK Cl- CotransportersMiceMice, TransgenicMotor NeuronsNeural InhibitionSpinal CordSuperoxide Dismutase-1Chloridesgamma-Aminobutyric AcidGlycineK Cl- CotransportersSod1 protein, mouseSuperoxide Dismutase-1SymportersALS diseaseGABA/glycine inhibitionmodellingmouseneurosciencepatch-clamprelaxation time courseSOD1G93A

Identifiers

PMID31868588
PMCPMC6974356

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.