Evidence map›Paper›PMID 31868164›Full record

ArticleeLife2019

Acute cerebellar knockdown of

Samantha Washburn, Rachel Fremont, Maria Camila Moreno-Escobar, Chantal Angueyra, Kamran Khodakhah

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 40 citations in OpenAlex.

  1. Distinct Brain Drivers and Shared Cerebello-Cortical Input in ADCY5 and SGCE Hyperkinetic Movements.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
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  4. Review
  5. Article
  6. Sex-specific alterations of Purkinje cell firing inDystonia (Lausanne, Switzerland) · 2025
    Article
  7. Article
  8. Review
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  10. Article
  11. Article
  12. Article
  13. Review
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  15. Review
  16. Review
  17. Article
  18. Striatal Indirect Pathway Dysfunction Underlies Motor Deficits in a Mouse Model of Paroxysmal Dyskinesia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Samantha WashburnDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, United States.ORCID 0000-0001-8317-1558
Rachel FremontDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, United States.
Maria Camila Moreno-EscobarDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, United States.
Chantal AngueyraDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, United States.
Kamran KhodakhahDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, United States.ORCID 0000-0001-7905-5335
Albert Einstein College of Medicine · US

Funding

Cerebellar Dysfunction in DYT1R01NS105470 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KHODAKHAH, KAMRAN · 2018 to 2022
$2.3M
Cerebellar Involvement and Alcohol Effects in a Mouse Model of Myoclonus DystoniaF31NS089716 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KEE, SAMANTHA · 2014 to 2016
$129k
NINDS NIH HHS NS089716NINDS NIH HHS NS105470
6 · The paper itself

Abstract

Myoclonus dystonia (DYT11) is a movement disorder caused by loss-of-function mutations in

Indexed as

AnimalsCerebellar CortexCerebellumDisease Models, AnimalDystoniaDystonic DisordersEthanolFemaleGangliaGenetic Predisposition to DiseaseMaleMiceMice, Inbred C57BLMice, KnockoutRNA, Small InterferingSarcoglycansEthanolRNA, Small InterferingSarcoglycansalcohol responsive dystoniaDYT11mousemyoclonus dystonianeuroscience

Identifiers

PMID31868164
PMCPMC6959989
OpenAlexW2994891117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.