Evidence map›Paper›PMID 31867769›Full record

ArticleJournal of applied toxicology : JAT2020

Measurement of the penetration of 56 cosmetic relevant chemicals into and through human skin using a standardized protocol.

Nicola J Hewitt, Sébastien Grégoire, Richard Cubberley, Hélène Duplan, Joan Eilstein, Corie Ellison, Cathy Lester, Eric Fabian, Julien Fernandez, Camille Géniès and 6 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Journal of applied toxicology : JAT, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
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  4. LION Data: A roaring transformation in data visualisation.Computers & chemical engineering · 2025
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  13. Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro.Toxicology in vitro : an international journal published in association with BIBRA · 2023
    Article
  14. Article
  15. Review
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  17. Article
  18. Article
  19. UV-filter pollution: current concerns and future prospects.Environmental monitoring and assessment · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 5 countries.

Nicola J HewittADME Task Force, Cosmetics Europe, Brussels, Belgium.ORCID 0000-0002-1045-0748
Sébastien GrégoireL'Oreal Research and Innovation, Aulnay-Sous-Bois, France.
Richard CubberleyUnilever, Bedfordshire, UK.
Hélène DuplanPierre Fabre Dermo-Cosmétique, Toulouse, France.
Joan EilsteinL'Oreal Research and Innovation, Aulnay-Sous-Bois, France.
Corie EllisonThe Procter and Gamble Company, Cincinnati, Ohio.
Cathy LesterThe Procter and Gamble Company, Cincinnati, Ohio.
Eric FabianBASF, Ludwigshafen, Germany.
Julien FernandezEurofins I ADME Bioanalysis, Vergeze, France.
Camille GénièsPierre Fabre Dermo-Cosmétique, Toulouse, France.
Carine Jacques-JaminPierre Fabre Dermo-Cosmétique, Toulouse, France.
Martina KlaricADME Task Force, Cosmetics Europe, Brussels, Belgium.
Helga RotheProcter and Gamble (currently Coty), Darmstadt, Germany.
Ian SorrellUnilever, Bedfordshire, UK.
Daniela LangeBeiersdorf AG, Hamburg, Germany.
Andreas SchepkyBeiersdorf AG, Hamburg, Germany.
Pierre Fabre (France) · FRBeiersdorf (Germany) · DECosmetics Europe · BEL'Oréal (France) · FRProcter & Gamble (United States) · USUnilever (United Kingdom) · GBBASF (Germany) · DEEurofins (France) · FRProcter & Gamble (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

OECD test guideline 428 compliant protocol using human skin was used to test the penetration of 56 cosmetic-relevant chemicals. The penetration of finite doses (10 μL/cm

Indexed as

Skin AbsorptionAdministration, CutaneousAdultAgedCosmeticsEthanolFemaleHumansKineticsMaleMiddle AgedSkinSolubilitySolventsYoung AdultCosmeticsEthanolSolventscosmetic ingredientsdatasetdermal deliveryharmonizedhuman skinpenetration

Identifiers

PMID31867769
PMCPMC7027575
OpenAlexW2995352483

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.