Evidence map›Paper›PMID 31867757›Full record

ArticleJournal of clinical laboratory analysis2020

A risk scoring system for the decreased glomerular filtration rate in Chinese general population.

Yan Gu, Min Chen, Bei Zhu, Xiaohua Pei, Zhenzhu Yong, Xiaona Li, Qun Zhang, Weihong Zhao

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yan GuDivision of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Min ChenDivision of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Bei ZhuDivision of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiaohua PeiDivision of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zhenzhu YongDivision of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiaona LiHealth Management Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qun ZhangHealth Management Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Weihong ZhaoDivision of Nephrology, Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0001-8211-2900
Jiangsu Province Hospital · CNNantong University · CN

Funding

Jiangsu Provincial Key Discipline of Medicine ZDXKA2016003Jiangsu Provincial Key Talent Program of Medicine ZDRCA2016021Jiangsu Provincial Medical Young Talent Program QNRC2016592Jiangsu Provincial Scientific Research of Cadre Health Care BJ16016Jiangsu Provincial Scientific Research of Cadre Health Care BJ17018Jiangsu Provincial Talent Program of 333 Project BRA2017409
6 · The paper itself

Abstract

objectiveThe aim of this study was to establish a risk scoring system for the decreased glomerular filtration rate (GFR) in Chinese general population.

methodsTotally 781 participants who underwent a health checkup in The First Affiliated Hospital of Nanjing Medical University from January to September 2017 were involved in the study. Significant variables chosen by multivariable logistic regression analysis were allocated the integral scores in proportion to its odds ratio (OR), and then the risk of decreased GFR was assessed based on the scores.

resultsThe people with abnormal homocysteine (Hcy) level (OR: 1.534, 95% confidential interval [CI]: 1.075-2.190, P = .018), males (OR: 2.054, 95%CI: 1.365-3.092, P < .001), and those at the age of 46-52 years (OR: 2.943, 95%CI: 1.546-5.605, P = .001), 52-59 years (OR: 3.664, 95%CI: 1.937-6.931, P < .001) and ≥59 years (OR: 13.452, 95%CI: 7.339-24.657, P < .001) were subjected to GFR reduction. These three variables were allocated the integral scores in proportion to its OR, and four risk categories were divided according to the scores. The prevalence of the decreased GFR in people with low (score 0-4, n = 8), below the average (score 4-6, n = 37), above the average (score 6-13, n = 47), and high risks (score ≥ 13, n = 103) was 5.26%, 16.89%, 22.93% and 50.24%, respectively, and this prevalence raised with the increase of scores (P < .001).

conclusionsA risk scoring system is developed in this study, which may offer a specific risk stratification for GFR reduction in Chinese general population.

Indexed as

Asian PeopleAdultAgedAged, 80 and overFemaleGlomerular Filtration RateHumansLogistic ModelsMaleMiddle AgedModels, BiologicalMultivariate AnalysisPrevalenceRisk FactorsROC CurveChinese populationchronic kidney diseaseglomerular filtration ratehomocysteinerisk score

Identifiers

PMID31867757
PMCPMC7171293
OpenAlexW2998057951

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.