Evidence map›Paper›PMID 31867563›Full record

ArticleNanoscale advances2019

Quantum Dot Cellular Uptake and Toxicity in the Developing Brain: Implications for Use as Imaging Probes.

Mengying Zhang, Brittany P Bishop, Nicole L Thompson, Kate Hildahl, Binh Dang, Olesya Mironchuk, Nina Chen, Reyn Aoki, Vincent C Holmberg, Elizabeth Nance

Open access · goldAbstract read
In one paragraph

Article in Nanoscale advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 53 citations in OpenAlex.

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  6. Nanotherapeutics and the Brain.Annual review of chemical and biomolecular engineering · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Mengying ZhangMolecular Engineering & Sciences Institute, University of Washington, Seattle, WA 98195-1652, United States.
Brittany P BishopDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195-1750, United States.
Nicole L ThompsonDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195-1750, United States.
Kate HildahlDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195-1750, United States.
Binh DangDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195-1750, United States.
Olesya MironchukDepartment of Bioengineering, University of Washington, Seattle, WA 98195-5061, United States.
Nina ChenDepartment of Biology, University of Washington, Seattle, WA 98195-1800, United States.
Reyn AokiDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195-1750, United States.
Vincent C HolmbergMolecular Engineering & Sciences Institute, University of Washington, Seattle, WA 98195-1652, United States.
Elizabeth NanceMolecular Engineering & Sciences Institute, University of Washington, Seattle, WA 98195-1652, United States.
University of Washington · US

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Sheela Sathyanarayana · 1995 to 2026
$42.5M
Quantitative 3D imaging of in situ nanoparticle movement and cellular behavior during neuroinflammationR35GM124677 · NIGMS · UNIVERSITY OF WASHINGTON · PI NANCE, ELIZABETH A · 2017 to 2022
$2.5M
NIEHS NIH HHS P30 ES007033NIGMS NIH HHS R35 GM124677
6 · The paper itself

Abstract

Nanometer-sized luminescent semiconductor quantum dots (QDs) have been utilized as imaging and therapeutic agents in a variety of disease settings, including diseases of the central nervous system. QDs have several advantages over traditional fluorescent probes including their small size (5-10 nm), tunable excitation and emission spectra, tailorable surface functionality, efficient photoluminescence, and robust photostability, which are ideal characteristics for

Indexed as

colloidal stabilitymetallothioneinmicroglial uptakenanoscale probesneuroimagingorganotypic brain slicequantum dots

Identifiers

PMID31867563
PMCPMC6924642
OpenAlexW2966200923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.