SynthesisFrontiers in public health2019
Outdoor Air Pollution and Brain Structure and Function From Across Childhood to Young Adulthood: A Methodological Review of Brain MRI Studies.
Synthesis in Frontiers in public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 5 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Ambient Air Pollution and Risk of Brain Tumors: A Systematic Review and Meta-Analysis.Asian Pacific journal of cancer prevention : APJCP · 2026Pooled it
- A systematic review of air pollution exposure and brain structure and function during development.Environmental research · 2025Pooled it
- Prenatal Exposure to Air Pollutants and Attentional Deficit Hyperactivity Disorder Development in Children: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- Toxicant exposure and the developing brain: A systematic review of the structural and functional MRI literature.Neuroscience and biobehavioral reviews · 2023Pooled it
- Air pollution, depressive and anxiety disorders, and brain effects: A systematic review.Neurotoxicology · 2022Pooled it
- Green space is associated with better directed attention and higher crystallized intelligence in middle childhood: Evidence from the ABCD study.Environment international · 2026Article
- The Relationship between Air Pollution Exposure, Genetic Liability for Schizophrenia, and Brain Outcomes in the ABCD Study.Schizophrenia bulletin · 2026Article
- Revisiting 'environmental effects': Directions for multidisciplinary investigations of air quality and psychopathology.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Neighborhood air pollution is associated with attenuated neurocognitive maturation over early adolescence.Developmental cognitive neuroscience · 2026Article
- Feasibility of Integrating Wearable Devices and Ecological Momentary Assessment for Real-Time Environmental Exposure Estimation: Proof-of-Concept Study.JMIR formative research · 2026Article
- White matter reflects the childhood exposome.bioRxiv : the preprint server for biology · 2026Article
- Characteristics of Cognitive Function and Brain Alterations in Pneumoconiosis: A Cross-Sectional Study.Health science reports · 2026Article
- Childhood Opportunity Index 2.0 and Cognition via the NIH Toolbox.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026Article
- In utero air pollution exposure and pre- and postnatal brain development: a review.Neuroscience applied · 2026Review
- Exposure to consecutive extreme ozone-heatwave events and neurological disorders: a retrospective cohort study in Nanjing, China.Environmental health : a global access science source · 2025Article
- The Impact of Early Life Exposure to Air Pollution on the Brain: A Diffusion MRI Study in 10-13-Year-Old Children With and Without ADHD Diagnosis.Human brain mapping · 2025Article
- Sources and components of fine air pollution exposure and brain morphology in preadolescents.The Science of the total environment · 2025Article
- Air Pollution Exposure, Prefrontal Connectivity, and Emotional Behavior in Early Adolescence.Research report (Health Effects Institute) · 2025Article
- The Childhood Opportunity Index 2.0: Factor Structure in 9-10 Year Olds in the Adolescent Brain Cognitive Development Study.International journal of environmental research and public health · 2025Article
- Functional Brain Connectivity Predictors of Prospective Substance Use Initiation and Their Environmental Correlates.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Outdoor air pollution has been recognized as a novel environmental neurotoxin. Studies have begun to use brain Magnetic Resonance Imaging (MRI) to investigate how air pollution may adversely impact developing brains. A systematic review was conducted to evaluate and synthesize the reported evidence from MRI studies on how early-life exposure to outdoor air pollution affects neurodevelopment. Using PubMed and Web of Knowledge, we conducted a systematic search, followed by structural review of original articles with individual-level exposure data and that met other inclusion criteria. Six studies were identified, each sampled from 3 cohorts of children in Spain, The Netherlands, and the United States. All studies included a one-time assessment of brain MRI when children were 6-12 years old. Air pollutants from traffic and/or regional sources, including polycyclic aromatic hydrocarbons (PAHs), nitrogen dioxide, elemental carbon, particulate matter (<2.5 or <10 μm), and copper, were estimated prenatally (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.