Evidence map›Paper›PMID 31867132›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2019

Clinical Profile of Non-Motor Symptoms in Patients with Essential Tremor: Impact on Quality of Life and Age-Related Differences.

Ali S Shalash, Hadeer Mohamed, Alia H Mansour, Ahmed Elkady, Hanan Elrassas, Eman Hamid, Mahmoud H Elbalkimy

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05170022 (Clinical Profile in Patients With Essential Tremors), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05170022 unknown statusnot on this mapstarted 2022, after this paper: background citation

Clinical Profile in Patients With Essential Tremors

TypeobservationalSponsorAssiut UniversityRan2022 to 2025Enrolled30ConditionsEssential Tremor
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Clinical Features of Essential Tremor and its Impact on Quality of Life in Japan.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Diagnosis and Treatment of Essential Tremor.Continuum (Minneapolis, Minn.) · 2022
    Review
  10. Article
  11. Article
  12. Genomic Markers for Essential Tremor.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  13. Article
  14. Sleep Disorders in Patients with Essential Tremor.Current neurology and neuroscience reports · 2021
    Review
  15. Article
  16. Essential tremor: Is the word "essential" really essential?Parkinsonism & related disorders · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ali S ShalashDepartment of Neurology, Faculty of Medicine, Ain Shams University, Cairo, EG.
Hadeer MohamedDepartment of Neurology, Faculty of Medicine, Ain Shams University, Cairo, EG.
Alia H MansourDepartment of Neurology, Faculty of Medicine, Ain Shams University, Cairo, EG.
Ahmed ElkadyDepartment of Neurology, Faculty of Medicine, Ain Shams University, Cairo, EG.
Hanan ElrassasOkasha Institute of Psychiatry, Ain Shams University, Cairo, EG.
Eman HamidDepartment of Neurology, Faculty of Medicine, Ain Shams University, Cairo, EG.
Mahmoud H ElbalkimyDepartment of Neurology, Faculty of Medicine, Ain Shams University, Cairo, EG.
Ain Shams University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Identifying the clinical phenotypes of non-motor symptoms (NMSs) of essential tremor (ET) among different populations is necessary due to their impact on the quality of life (QoL). This study aimed to investigate the clinical phenotype and impact of NMSs on QoL in Egyptian patients with ET. Methods: Thirty ET patients were compared to 30 matched controls. Subjects were evaluated by the Fahn-Tolosa-Marin Tremor Rating Scale, Non-Motor Symptoms Scale (NMSS), Montreal Cognitive Assessment, Hamilton Anxiety Rating Scale, Beck Depression Inventory, Pittsburgh Sleep quality Index, and the Short Form 36 Health Survey Questionnaire. Both groups were divided into two subgroups of younger ( Results: ET patients showed significantly worse cognition, depression, anxiety, sleep and NMSS domains (p Discussion: The study supports that NMSs are integral part of ET, negatively affect QoL, and similarly affect younger and older patients. Therefore, NMSs should be explored for proper care of ET patients.

Indexed as

Health SurveysAdolescentAdultAgedAge FactorsCase-Control StudiesEssential TremorFemaleHumansMaleMiddle AgedQuality of LifeYoung Adultcognitive deficitEssential tremornon-motor symptomsquality of lifesleep quality

Identifiers

PMID31867132
PMCPMC6898893
OpenAlexW3003097529

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.