Evidence map›Paper›PMID 31867000›Full record

ReviewFrontiers in immunology2019

Arid5a Regulation and the Roles of Arid5a in the Inflammatory Response and Disease.

Kishan Kumar Nyati, Riddhi Girdhar Agarwal, Praveen Sharma, Tadamitsu Kishimoto

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 61 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Kishan Kumar NyatiLaboratory of Immune Regulation, Immunology Frontier Research Center, Osaka University, Osaka, Japan.
Riddhi Girdhar AgarwalDepartment of Biochemistry, All India Institute of Medical Sciences, Jodhpur, India.
Praveen SharmaDepartment of Biochemistry, All India Institute of Medical Sciences, Jodhpur, India.
Tadamitsu KishimotoLaboratory of Immune Regulation, Immunology Frontier Research Center, Osaka University, Osaka, Japan.
All India Institute of Medical Sciences Jodhpur · INOsaka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abnormal gene expression patterns underlie many diseases that represent major public health concerns and robust therapeutic challenges. Posttranscriptional gene regulation by RNA-binding proteins (RBPs) is well-recognized, and the biological functions of RBPs have been implicated in many diseases, such as autoimmune diseases, inflammatory diseases, and cancer. However, a complete understanding of the regulation mediated by several RBPs is lacking. During the past few years, a novel role of AT-rich interactive domain-containing protein 5a (Arid5a) as an RBP is being investigated in the field of immunology owing to binding of Arid5a protein to the 3' untranslated region (UTR) of

Indexed as

Disease SusceptibilityAnimalsBiomarkersDNA-Binding ProteinsGene Expression ProfilingHumansInflammationRNA, MessengerRNA Processing, Post-TranscriptionalRNA StabilityToll-Like Receptor 4ARID5A protein, humanBiomarkersDNA-Binding ProteinsRNA, MessengerToll-Like Receptor 4Arid5aimmune regulationinflammationmRNA stabilityposttranscriptional regulationTLR4

Identifiers

PMID31867000
PMCPMC6906145
OpenAlexW2985523113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.