Evidence map›Paper›PMID 31866965›Full record

ArticleFrontiers in microbiology2019

The Lysine Deacetylase RpdA Is Essential for Virulence in

Ingo Bauer, Matthias Misslinger, Yana Shadkchan, Anna-Maria Dietl, Verena Petzer, Thomas Orasch, Beate Abt, Stefan Graessle, Nir Osherov, Hubertus Haas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  3. Recent developments inMicrobiology and molecular biology reviews : MMBR · 2025
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  8. Regulation of Transgene Expression by the Natural Sweetener Xylose.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  9. Characterization and engineering of the xylose-inducibleMetabolic engineering communications · 2022
    Article
  10. Review
  11. Article
  12. Review
  13. Inducible Selectable Marker Genes to ImproveJournal of fungi (Basel, Switzerland) · 2021
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Ingo BauerInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Matthias MisslingerInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Yana ShadkchanDepartment of Clinical Microbiology and Immunology, Aspergillus and Antifungal Research Laboratory, Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel.
Anna-Maria DietlInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Verena PetzerDepartment of Internal Medicine II (Infectious Diseases, Immunology, Rheumatology and Pneumology), Medical University of Innsbruck, Innsbruck, Austria.
Thomas OraschInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Beate AbtInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Stefan GraessleInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Nir OsherovDepartment of Clinical Microbiology and Immunology, Aspergillus and Antifungal Research Laboratory, Sackler School of Medicine, Tel Aviv University, Tel Aviv-Yafo, Israel.
Hubertus HaasInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Universität Innsbruck · ATInnsbruck Medical University · ATTel Aviv University · IL

Funding

Austrian Science Fund FWF P 24803Austrian Science Fund FWF W 1253
6 · The paper itself

Abstract

Current suboptimal treatment options of invasive fungal infections and emerging resistance of the corresponding pathogens urge the need for alternative therapy strategies and require the identification of novel antifungal targets.

Indexed as

Aspergillus fumigatusconditional in vivo expressionHDACKDACmurine virulence modelRpdAxylosexylP

Identifiers

PMID31866965
PMCPMC6905131
OpenAlexW2992992625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.