ArticleFrontiers in physiology2019
Age-Related Structural and Functional Changes in the Mouse Lung.
Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
52 citing papers in PubMed, 93 citations in OpenAlex.
- Functional micro-computed tomography requires baseline characterisation to accurately describe quantitative lung parenchymal changes.Breathe (Sheffield, England) · 2026Article
- Multiorgan transcriptomics and circulating extracellular vesicle profiling reveal age-dependent systemic vulnerability to isoflurane anesthesia and surgery.GeroScience · 2026Article
- Age-Dependent Correlation of Pulmonary Function Impairment and Aortic Arch Stiffness in Mice.Pediatric discovery · 2026Article
- Addressing Sex as a Biological Variable in Preclinical Models of Lung Disease: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2025Article
- Sex- and age-related differences in LPS-induced lung injury: establishing a mouse intensive care unit.Intensive care medicine experimental · 2025Article
- Micromechanics of lung capillaries across mouse lifespan and in positive- vs negative-pressure ventilation.npj biological physics and mechanics · 2025Article
- Quantitative micro-CT-derived biomarkers elucidate age-related lung fibrosis in elder mice.Respiratory research · 2024Article
- Functional and Structural Changes in Diaphragm Neuromuscular Junctions in Early Aging.International journal of molecular sciences · 2024Article
- Aging drives cerebrovascular network remodeling and functional changes in the mouse brain.Nature communications · 2024Article
- MMP-3 mediates copper oxide nanoparticle-induced pulmonary inflammation and fibrosis.Journal of nanobiotechnology · 2024Article
- Characterization of dUTPase expression in mouse postnatal development and adult neurogenesis.Scientific reports · 2024Article
- Developmental changes in lung function of mice are independent of sex as a biological variable.American journal of physiology. Lung cellular and molecular physiology · 2024Article
- The Role of the Redox Enzyme p66Shc in Biological Aging of the Lung.Aging and disease · 2024Article
- Article
- Mapping the strain-stiffening behavior of the lung and lung cancer at microscale resolution using the crystal ribcage.Frontiers in network physiology · 2024Article
- Age-related lung changes linked to altered lysosomal protease profile, histology, and ultrastructure.PloS one · 2024Article
- Lung Ultrasound Score as a Predictor of Failure to Wean COVID-19 Elderly Patients off Mechanical Ventilation: A Prospective Observational Study.Clinical interventions in aging · 2024Observational
- A genomic perspective of the aging human and mouse lung with a focus on immune response and cellular senescence.Immunity & ageing : I & A · 2023Article
- Crystal ribcage: a platform for probing real-time lung function at cellular resolution.Nature methods · 2023Article
- LungElast-an open-source, flexible, low-cost, microprocessor-controlled mouse lung elastometer.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lung function declines with advancing age. To improve our understanding of the structure-function relationships leading to this decline, we investigated structural alterations in the lung and their impact on micromechanics and lung function in the aging mouse. Lung function analysis was performed in 3, 6, 12, 18, and 24 months old C57BL/6 mice (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.