Evidence map›Paper›PMID 31866863›Full record

ArticleFrontiers in pharmacology2019

Discovery of Novel Doxorubicin Metabolites in MCF7 Doxorubicin-Resistant Cells.

Xu Wang, Renjie Hui, Yun Chen, Wentao Wang, Yujiao Chen, Xiaohai Gong, Jian Jin

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
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  8. Intra-tumoral drug concentration mapping within solid tumor micro-milieu using in-vitro model and doxorubicin as a model drug.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xu WangSchool of Pharmaceutical Sciences, Jiangnan University, Wuxi, China.
Renjie HuiSchool of Pharmaceutical Sciences, Jiangnan University, Wuxi, China.
Yun ChenSchool of Pharmaceutical Sciences, Jiangnan University, Wuxi, China.
Wentao WangSchool of Pharmaceutical Sciences, Jiangnan University, Wuxi, China.
Yujiao ChenSchool of Pharmaceutical Sciences, Jiangnan University, Wuxi, China.
Xiaohai GongSchool of Pharmaceutical Sciences, Jiangnan University, Wuxi, China.
Jian JinSchool of Pharmaceutical Sciences, Jiangnan University, Wuxi, China.
Jiangnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Doxorubicin (DOX) is metabolized to a variety of metabolites

Indexed as

breast cancerdoxorubicindrug resistantintracellular drug metabolismLC-MS/MS

Identifiers

PMID31866863
PMCPMC6909010
OpenAlexW2994348985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.