ArticleFrontiers in aging neuroscience2019
Predictive Value of Routine Peripheral Blood Biomarkers in Alzheimer's Disease.
Article in Frontiers in aging neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.
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Who cites it
67 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association between mean platelet volume and obstructive sleep apnea-hypopnea syndrome: A systemic review and meta-analysis.PloS one · 2024Pooled it
- Neutrophil to lymphocyte ratio in Alzheimer's disease: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Association of Peripheral Blood Cell Profile With Alzheimer's Disease: A Meta-Analysis.Frontiers in aging neuroscience · 2022Pooled it
- Common and distinct plasma proteomic signature of aerobic and motor physical activity interventions and their link to episodic memory.GeroScience · 2026Article
- Article
- Mild cognitive impairment cases affect the predictive power of Alzheimer's disease diagnostic models using routine clinical variables.npj aging · 2026Article
- Interplay between Peripheral and Central Nervous System Myeloid Cells during Aging: Impact for Lade-Life Depression and Alzheimer's Disease.Neuroimmunomodulation · 2026Review
- The impact of Naples prognostic score on cognitive impairment in hemodialysis patients: a multicenter study.Renal failure · 2025Article
- The role of neutrophils, red blood cells, and platelets in the pathology of Alzheimer's disease.Annals of medicine · 2025Review
- White Blood Cells in Neurodegenerative Diseases in the Context of Neuroinflammation.Molecular neurobiology · 2025Review
- Adaptive immunity in the neuroinflammation of Alzheimer's disease.Chinese medical journal · 2025Review
- Modeling trajectories of routine blood tests as dynamic biomarkers for outcome in spinal cord injury.NPJ digital medicine · 2025Article
- Predictive value of peripheral blood inflammatory markers for epilepsy occurrence in traumatic brain injury patients.Acta epileptologica · 2025Article
- Adaptive Immune Dyshomeostasis as a Mediator of Vascular Cognitive Decline: Unraveling Neurovascular Crosstalk.Aging and disease · 2025Review
- Associations between platelet indices and cerebrospinal fluid biomarkers of Alzheimer's disease pathology in cognitively intact adults: the CABLE study.Alzheimer's research & therapy · 2025Article
- Neutrophil-to-Lymphocyte Ratio in the Alzheimer's Disease Continuum.International journal of molecular sciences · 2025Review
- Association of red blood cell count, hemoglobin concentration, and inflammatory indices with cognitive impairment severity in Alzheimer's disease.Scientific reports · 2025Article
- Article
- Dysregulated interleukin networks drive immune heterogeneity in Alzheimer's disease: an immunogenomic approach to subgroup classification and predictive modeling.BMC neurology · 2025Article
- Article
7 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBiomarker screening is of major significance for the early diagnosis and prevention of Alzheimer's disease (AD). Routine peripheral blood parameters are easy to collect and detect, making them ideal potential biomarkers. Thus, we aimed to evaluate the parameters from routine blood as potential biomarkers for AD.
methodsWe enrolled 56 AD patients, 57 mild cognitive impairment (MCI) patients, and 59 healthy elderly controls. Receiver operating characteristic (ROC) curves were used to assess the diagnostic values of routine blood biomarkers in patients with cognitive impairment.
resultsThere were significant differences in eight parameters between the groups. Logistic regression revealed that the neutrophil% (odds ratio (OR) 1.34, 95% confidence interval [CI] 1.03-1.75,
conclusionSome routine blood biomarkers may correlate with cognitive impairment. Analysis of these biomarkers, such as the NLR, may be useful for the identification of patients with cognitive impairment.
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