Evidence map›Paper›PMID 31866814›Full record

ArticleFrontiers in neuroscience2019

Dexamethasone Causes Hypertension in Rats Even Under Chemical Blockade of Peripheral Sympathetic Nerves.

Alexandra E Soto-Piña, Cynthia Franklin, C S Sheela Rani, Elizabeth Fernandez, Elías Cardoso-Peña, Alejandra D Benítez-Arciniega, Helmut Gottlieb, Carmen Hinojosa-Laborde, Randy Strong

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Alexandra E Soto-PiñaFacultad de Medicina, Universidad Autónoma del Estado de México, Toluca, Mexico.
Cynthia FranklinFeik School of Pharmacy, University of the Incarnate Word, San Antonio, TX, United States.
C S Sheela RaniDepartment of Pharmacology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Elizabeth FernandezDepartment of Pharmacology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Elías Cardoso-PeñaUnidad de Medicina Familiar 220, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Alejandra D Benítez-ArciniegaFacultad de Medicina, Universidad Autónoma del Estado de México, Toluca, Mexico.
Helmut GottliebFeik School of Pharmacy, University of the Incarnate Word, San Antonio, TX, United States.
Carmen Hinojosa-LabordeDepartment of Pharmacology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Randy StrongDepartment of Pharmacology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
The University of Texas Health Science Center at San Antonio · USUniversidad Autónoma del Estado de México · MXUniversity of the Incarnate Word · USMexican Social Security Institute · MXSouth Texas Veterans Health Care System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic glucocorticoids (GCs) are widely used to treat inflammatory conditions. However, chronic use of GCs can lead to hypertension. The cause of this undesired side effect remains unclear. Previously, we developed an

Indexed as

6-OHDAadrenal medulladexamethasonehypertensionrenal denervationsympathetic nerves

Identifiers

PMID31866814
PMCPMC6909820
OpenAlexW2992564085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.