Evidence map›Paper›PMID 31866460›Full record

ArticleAcademic pediatrics

Sources and Biomarkers of Secondhand Tobacco Smoke Exposure in Urban Adolescents.

Natalie Nardone, Shonul Jain, Newton Addo, Gideon St Helen, Peyton Jacob, Neal L Benowitz

Open access · greenAbstract read
In one paragraph

Article in Academic pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The Diverging Trend in Exposure to Environmental Tobacco Smoke Among US Children.Journal of racial and ethnic health disparities · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. The mutagenic effect of tobacco smoke on male fertility.Environmental science and pollution research international · 2022
    Review
  8. Cross-sectional study of urinary biomarkers of environmental tobacco and e-cigarette exposure and asthma morbidity.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Article
  9. Article
  10. Comparison of Levels of Three Tobacco Smoke Exposure Biomarkers in Children of Smokers.International journal of environmental research and public health · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Natalie NardoneDivision of Cardiology, Department of Medicine, Program in Clinical Pharmacology, University of California San Francisco (N Nardone, N Addo, and G St.Helen). Electronic address: natalie.nardone@ucsf.edu.
Shonul JainDepartment of Pediatrics, University of California San Francisco (S Jain).
Newton AddoDivision of Cardiology, Department of Medicine, Program in Clinical Pharmacology, University of California San Francisco (N Nardone, N Addo, and G St.Helen).
Gideon St HelenDivision of Cardiology, Department of Medicine, Program in Clinical Pharmacology, University of California San Francisco (N Nardone, N Addo, and G St.Helen); Center for Tobacco Control Research and Education, University of California San Francisco (G St.Helen and NL Benowitz).
Peyton JacobDivision of Cardiology, Departments of Medicine and Psychiatry, Clinical Pharmacology Research Laboratory, University of California San Francisco (P Jacob).
Neal L BenowitzCenter for Tobacco Control Research and Education, University of California San Francisco (G St.Helen and NL Benowitz); Department of Medicine and Bioengineering and Therapeutic Sciences, University of California San Francisco (NL Benowitz).
University of California, San Francisco · US

Funding

Research Support CoreP30DA012393 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ST.HELEN, GIDEON · 1999 to 2024
$17.1M
Liquid Chromatograph-Triple Quadrupole Mass SpectrometerS10RR026437 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JACOB, PEYTON · 2010 to 2010
$448k
NCRR NIH HHS S10 RR026437NIDA NIH HHS P30 DA012393
6 · The paper itself

Abstract

objectiveIn an urban adolescent population, we evaluated sources of exposure to secondhand smoke exposure (SHS), examined differences in exposure by race/ethnicity, age and sex, and determined the relationship between exposure source(s) and the biomarkers cotinine and NNAL.

methodsParticipants were recruited from a public hospital-based outpatient clinic in San Francisco, CA, USA.

resultsOf a sample of N = 298 adolescents screened, 235 were biologically confirmed to be exposed to tobacco smoke. Of those, N = 16 were active smokers and N = 219 were exposed to SHS; 91 (39%) were heavily SHS exposed (median cotinine = 0.76 ng/mL) and 128 (54%) had light SHS exposure (median cotinine = 0.11 ng/mL). Within those SHS exposed, the most common source of exposure was in a public area. No significant racial/ethnic differences were found, although African American adolescents were more likely to live in a home that allowed smoking. Older adolescents were more likely to be exposed across several difference sources, and females more likely to be exposed in a car and in public areas. Past 7-day exposure in the home, in a car, and current blunt use were significantly related to biomarkers of exposure.

conclusionsUrban adolescents are exposed to SHS across a variety of sources. Although exposure in a public area is most common, exposure in the home and in cars significantly influences tobacco biomarker levels. Interventions to reduce exposure would have the greatest impact in this population if they focused on reducing exposure in the home and in cars. History of blunt use is a strong determinant of tobacco exposure.

Indexed as

Tobacco Smoke PollutionAdolescentBiomarkersCotinineEnvironmental ExposureFemaleHumansSmokingUrban PopulationBiomarkersCotinineTobacco Smoke Pollutionadolescentscotininesecondhand smokesensitive populations

Identifiers

PMID31866460
PMCPMC7967984
OpenAlexW2995899980

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.