Evidence map›Paper›PMID 31866349›Full record

ReviewThe American journal of pathology2020

Endothelial Cell Calcium Signaling during Barrier Function and Inflammation.

Prarthana J Dalal, William A Muller, David P Sullivan

Open access · bronzeAbstract readReview
In one paragraph

Review in The American journal of pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 227 citations in OpenAlex.

  1. Article
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  4. Skin capillary endothelial cells form a network of spatiotemporally conserved CaProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
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  7. Guidelines for evaluating endothelial function in vascular tissue.American journal of physiology. Heart and circulatory physiology · 2026
    Review
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  9. Article
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  12. Article
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  15. Review
  16. Role of neutrophils in regulating vascular permeability in inflammatory and autoimmune diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  17. Review
  18. Review
  19. Review
  20. Protocol for Cryopreservation of Endothelial Monolayers: An Update.Methods in molecular biology (Clifton, N.J.) · 2026
    Article

77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Prarthana J DalalDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
William A MullerDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
David P SullivanDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address: d-sullivan@northwestern.edu.
Northwestern University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008152 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ARDEHALI, HOSSEIN · 1987 to 2021
$24.0M
Medical Scientist Training ProgramT32GM144295 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ALAN R HAUSER · 2022 to 2026
$9.1M
TWO NOVEL VASCULAR ADHESION MOLECULES: PECAM AND HEC-1R01HL046849 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MULLER, WILLIAM A · 1991 to 2019
$6.7M
PECAM-INDEPENDENT TRANSENDOTHELIAL MIGRATIONR01HL064774 · NHLBI · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI MULLER, WILLIAM A · 2000 to 2020
$3.3M
Defining the Role of IQGAP1 in Leukocyte Transmigration in vitro and in vivoF30HL134202 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DALAL, PRARTHANA · 2016 to 2020
$220k
NHLBI NIH HHS F30 HL134202NHLBI NIH HHS R01 HL046849NHLBI NIH HHS R01 HL064774NIGMS NIH HHS T32 GM008152NIGMS NIH HHS T32 GM144295
6 · The paper itself

Abstract

Calcium is an essential second messenger in endothelial cells and plays a pivotal role in regulating a number of physiologic processes, including cell migration, angiogenesis, barrier function, and inflammation. An increase in intracellular Ca

Indexed as

Calcium SignalingInflammationCell AdhesionCell CommunicationCell MovementCytoskeletonEndothelial CellsHumansLeukocyte RollingThrombinTransendothelial and Transepithelial MigrationThrombin

Identifiers

PMID31866349
PMCPMC7074364
OpenAlexW2994635858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.