ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2020
Adverse Experience Reports of Seizures in Youth and Young Adult Electronic Nicotine Delivery Systems Users.
Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 48 citations in OpenAlex.
- E-cigarette use among adults in southern Iran: a qualitative study.BMC public health · 2026Article
- Cognitive confusion: A cross-sectional study on the cognitive differences between traditional tobacco and e-cigarettes among college students in Zhejiang Province, China.Tobacco induced diseases · 2026Article
- Comparing vape use and perceptions among pharmacy and non-pharmacy students from two universities in the US and UK.Journal of preventive medicine and hygiene · 2025Article
- Epilepsy and nicotine use: Exploring disparities in ENDS and cigarette use among US adults with epilepsy.Epilepsy & behavior : E&B · 2025Article
- Differences in young adults' perceptions of e-cigarettes by history of use.Journal of American college health : J of ACH · 2024Article
- Cigarettes and e-cigarettes use among US adults with multimorbidity.Drug and alcohol dependence reports · 2024Article
- Vaping: Public Health, Social Media, and Toxicity.Online journal of public health informatics · 2024Article
- A clinical overview of adolescent e-cigarette use (vaping).Minerva pediatrics · 2024Article
- How do smoking, vaping, and nicotine affect people with epilepsy and seizures? A scoping review protocol.PloS one · 2023Article
- Article
- College Student E-Cigarette Users' Knowledge about E-Cigarettes: Ingredients, Health Risks, Device Modifications, and Information Sources.International journal of environmental research and public health · 2022Article
- Youth vaping: a review and update on global epidemiology, physical and behavioral health risks, and clinical considerations.European journal of pediatrics · 2022Review
- Stimulus functions of nicotine.Advances in pharmacology (San Diego, Calif.) · 2022Article
- Health effects and known pathology associated with the use of E-cigarettes.Toxicology reports · 2022Review
- Co-creating opportunities to incorporate cessation for electronic nicotine delivery systems in family medicine - a qualitative program evaluation.BMC family practice · 2021Article
- Burn injuries related to E-cigarettes reported to poison control centers in the United States, 2010-2019.Injury epidemiology · 2020Article
- Vaper, Beware: The Unique Toxicological Profile of Electronic Cigarettes.Environmental health perspectives · 2020Article
- Through the Haze: What Clinicians Can Do to Address Youth Vaping.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2020Article
- Socioeconomics of e-cigarette use in Colombia: 2019 National Substance Use Survey.Colombia medica (Cali, Colombia)Article
- Seizure Susceptibility in E-cigarette Users: Navigating the Clinical Management and Public Health Considerations.Substance use : research and treatmentReview
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeElectronic nicotine delivery systems (ENDS) use poses significant and avoidable health risks to young people. Until recently, seizures were most often associated with cases of liquid nicotine ingestion.
methodsWe examined 122 voluntary reports of seizures (n = 114) and neurological symptoms (syncope, n = 7; and tremor, n = 1) in 123 ENDS users (one report contained information on two users) received by the Food and Drug Administration between December 1, 2010, and June 30, 2019.
resultsThe median age (interquartile range) of users was 20 years (17-27); 67% of reports were in youth and young adults aged 14-24 years. Fifty-one (41%) reported other underlying medical conditions, including previous history of anxiety (n = 11), attention deficit hyperactivity disorder (n = 7), seizure (n = 6), and depression (n = 5). Of the 79 reports with available information, 67 (85%) reported seizure occurred within 24 hours of last use; 49 (62%) reported seizure within 30 minutes. The potential impact of concomitant use of marijuana or cannabidiol oil could not be evaluated from the eight reports that mentioned concomitant use.
conclusionsFindings suggest an association between ENDS use and seizures. Additional information will help to clarify the relationship between ENDS use and seizures and to understand how product attributes such as nicotine content, formulation, quantity, and other ingredients or contaminants may contribute to seizures. It is important that health care providers ask about ENDS use when evaluating neurological symptoms and that users, parents, school personnel, and health care providers report adverse experiences involving tobacco products to Food and Drug Administration via the Safety Reporting Portal (www.safetyreporting.hhs.gov).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.