Evidence map›Paper›PMID 31865868›Full record

ArticleClinical gerontologist

Depression Severity, but Not Cognitive Impairment or Frailty, is Associated with Disability in Late-Life Depression.

Ruth T Morin, Philip Insel, David Bickford, Craig Nelson, R Scott Mackin

Open access · greenAbstract read
In one paragraph

Article in Clinical gerontologist. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Ruth T MorinMental Health Service, Detroit VA Medical Center , Detroit, Michigan, USA.
Philip InselCenter for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center , San Francisco, California, USA.
David BickfordDepartment of Medicine, Medical College of Wisconsin , Milwaukee, Wisconsin, USA.
Craig NelsonDepartment of Psychiatry, University of California San Francisco , San Francisco, California, USA.
R Scott MackinCenter for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center , San Francisco, California, USA.
Lund University · SEMedical College of Wisconsin · USSan Francisco VA Medical Center · USUniversity of California, San Francisco · US

Funding

Cognitive and Neuroimaging Predictors of Disability in Late Life DepressionK08MH081065 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MACKIN, ROBERT SCOTT · 2008 to 2012
$877k
NIMH NIH HHS K08 MH081065
6 · The paper itself

Abstract

objectivesAssess the relationship of cognitive impairment to disability, accounting for depression severity and frailty, among older adults with late-life depression (LLD).

methodsData were analyzed from 78 community-dwelling older adults with LLD and without dementia (age

resultsThe average number of impaired cognitive tests was 2.0 (

conclusionsIn this sample, only depression severity was associated with increased disability. CLINICAL IMPLICATIONS: These findings have implications for intervention in LLD, as depression severity may represent a more modifiable risk factor for disability.

Indexed as

Cognitive DysfunctionDepressionFrailtyPersons with DisabilitiesAgedHumansNeuropsychological Testscognitive impairmentdisabilityfrailtyLate life depression

Identifiers

PMID31865868
PMCPMC9187219
OpenAlexW2996523227

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.