Evidence map›Paper›PMID 31865766›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

The Targeted Therapies Era Beyond the Surgical Point of View: What Spine Surgeons Should Know Before Approaching Spinal Metastases.

Fabio Cofano, Matteo Monticelli, Marco Ajello, Francesco Zenga, Nicola Marengo, Giuseppe Di Perna, Roberto Altieri, Paola Cassoni, Luca Bertero, Antonio Melcarne and 3 more

Abstract read
In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Clinical outcomes of the LORDS strategy for thoracolumbar spinal metastases: a retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fabio CofanoDipartimento di Neuroscienze, Neurosurgery, Universita degli Studi di Torino, Torino, Italy.ORCID https://orcid.org/0000-0003-0558-8838
Matteo MonticelliDipartimento di Neuroscienze, Neurosurgery, Universita degli Studi di Torino, Torino, Italy.
Marco AjelloDipartimento di Neuroscienze, Neurosurgery, Universita degli Studi di Torino, Torino, Italy.
Francesco ZengaDipartimento di Neuroscienze, Neurosurgery, Universita degli Studi di Torino, Torino, Italy.
Nicola MarengoDipartimento di Neuroscienze, Neurosurgery, Universita degli Studi di Torino, Torino, Italy.
Giuseppe Di PernaDipartimento di Neuroscienze, Neurosurgery, Universita degli Studi di Torino, Torino, Italy.
Roberto AltieriDipartimento di Neuroscienze, Neurosurgery, Universita degli Studi di Torino, Torino, Italy.
Paola CassoniDipartimento di Scienze Mediche, Pathology, Universita degli Studi di Torino, Torino, Italy.
Luca BerteroDipartimento di Scienze Mediche, Pathology, Universita degli Studi di Torino, Torino, Italy.ORCID https://orcid.org/0000-0001-9887-7668
Antonio MelcarneDipartimento di Neuroscienze, Neurosurgery, Universita degli Studi di Torino, Torino, Italy.
Fulvio TartaraAzienda Ospedaliero-Universitaria di Parma, Special surgery, Neurosurgery, Torino, Italy.
Alessandro DucatiDipartimento di Neuroscienze, Neurosurgery, Universita degli Studi di Torino, Torino, Italy.
Diego GarbossaDipartimento di Neuroscienze, Neurosurgery, Universita degli Studi di Torino, Torino, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last few years, the treatment of spinal metastases has significantly changed. This is due to the advancements in surgical technique, radiotherapy, and chemotherapy which have enriched the multidisciplinary management. Above all, the field of molecular biology of tumors is in continuous and prosperous evolution. In this review, the molecular markers and new approaches that have radically modified the chemotherapeutic strategy of the most common metastatic neoplasms will be examined together with clinical and surgical implications. The experience and skills of several different medical professionals are mandatory: an interdisciplinary oncology team represents the winning strategy in the treatment of patients with spinal metastases.

Indexed as

HumansNeoplasm MetastasisSpinal NeoplasmsSurgeonsbone metastasesbreast cancercancercancer treatmentcolorectal cancerlung cancerlymphomamelanomaNSCLCrenal cancer

Identifiers

PMID31865766
PMCPMC6728684

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.