Evidence map›Paper›PMID 31865455›Full record

ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2020

Carbon/PEEK nails: a case-control study of 22 cases.

Federico Sacchetti, Lorenzo Andreani, Michele Palazzuolo, Stephane Cherix, Enrico Bonicoli, Elisabetta Neri, Rodolfo Capanna

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Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Federico SacchettiDepartment of Orthopaedic and Trauma Surgery, University of Pisa, Via Paradisa, 2., 56124, Pisa, Italy. federico.sacchetti1989@gmail.com.ORCID http://orcid.org/0000-0003-1276-0624
Lorenzo AndreaniDepartment of Orthopaedic and Trauma Surgery, University of Pisa, Via Paradisa, 2., 56124, Pisa, Italy.
Michele PalazzuoloDepartment of Orthopaedic and Trauma Surgery, Hopital du Valais, Sion, Switzerland.
Stephane CherixDepartment of Orthopaedic and Trauma Surgery, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Enrico BonicoliDepartment of Orthopaedic and Trauma Surgery, University of Pisa, Via Paradisa, 2., 56124, Pisa, Italy.
Elisabetta NeriDepartment of Orthopaedic and Trauma Surgery, University of Pisa, Via Paradisa, 2., 56124, Pisa, Italy.
Rodolfo CapannaDepartment of Orthopaedic and Trauma Surgery, University of Pisa, Via Paradisa, 2., 56124, Pisa, Italy.
University of Pisa · ITHôpital du Valais · CHUniversity Hospital of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInterest around carbon/PEEK plates and nails has been raising. The elastic modulus close to the bone, the high load-carrying capacity and radiolucency make CFR/PEEK materials a potential breakthrough. In the literature, there are abundant data about CFR/PEEK plates in the treatment of proximal humerus, distal radius and distal fibula fractures. In patients affected by bone metastasis, CFR/PEEK nails were proved effective and safe with 12 months of follow-up. Very little is known about performances of CFR/PEEK nails in patients affected by other pathologies. PURPOSES: The aim of the study was to evaluate safety and efficacy of CFR/PEEK nails in the treatment of various pathological conditions. It was also investigated whatever radiolucency of this nails could lead to a more objective evaluation of bone callus or disease site. PATIENTS AND

methodsIn the study group were included 20 patients (22 bone segments) who underwent CFR/PEEK nail implantation (eight humerus, one tibia, nine femur and four knee arthrodesis). They were affected by pathological fractures, and in four cases, they required an arthrodesis of the knee. They were retrospectively evaluated considering nail failures and bone callus or disease progression (RUSH scores). Mean follow-up time was 11 months (min 6.8-max 20.3). In the control group were included patients treated with titanium nails in the same institution for the same pathologies. An interclass correlation coefficient (ICC) analysis was performed in both groups considering RUSH scores by two expert surgeon from two institution to assess whether radiolucency could lead to a more objective evaluation of disease or bone callus site.

resultsThe ICC of mean values between RUSH scores was 0.882 (IC 95%: 0.702-0.953) in the CFR/PEEK group, while it was 0.778 (IC 95%: 0.41-0.91) in the titanium group. Observers' evaluation showed a significantly higher obscuration by titanium nails than by CFR/PEEK nails. No osteosynthesis failures were reported in both groups.

conclusionsOur results confirm the safety of CFR/PEEK nails in the short-medium term. The radiolucency of these materials led our observers to perform more objective evaluations of bone callus formation or disease progression compared to the titanium group given the higher ICC. LEVEL OF EVIDENCE: III Case-control therapeutic study.

Indexed as

Bone NailsBone NeoplasmsBony CallusFemoral FracturesFracture Fixation, IntramedullaryHumeral FracturesTibial FracturesArthrodesisBenzophenonesBiocompatible MaterialsCarbon FiberDisease ProgressionElastic ModulusFemaleFractures, SpontaneousHumansBenzophenonesBiocompatible MaterialsCarbon FiberKetonespolyetheretherketonePolyethylene GlycolsPolymersBone callusCarbonCFR/PEEKFracture healingMetastasisNail

Identifiers

PMID31865455
OpenAlexW2995317288

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.