ReviewCancer chemotherapy and pharmacology2020
Looking beyond the audiogram in ototoxicity associated with platinum-based chemotherapy.
Review in Cancer chemotherapy and pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 39 citations in OpenAlex.
- Pre-treatment audiological and vestibular assessment in adults starting platinum-based chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Exercise prehabilitation for brain health and sensory-cognitive function: Mechanistic insights into brain-body interactions.Experimental physiology · 2026Review
- A retrospective audit of audiology encounters in patients undergoing Cisplatin treatment at a large Australian tertiary cancer care centre.Journal of cancer survivorship : research and practice · 2026Article
- Comparative Study of the Quality of Life of Patients With Ototoxicity Due to Platinum-Based Chemotherapy, With Hearing Aid Versus Those Without: Study Protocol for a Randomized Pilot Study-The PROTOTOX Study.JMIR research protocols · 2025Article
- Improving the usability of grading scales for drug-induced ototoxicity with a focus on real world data collection.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Monitoring Ototoxicity in Cancer Patients Undergoing Platinum-Based Chemotherapy and Radiation in Saudi Arabia: Challenges and Solutions.Journal of multidisciplinary healthcare · 2025Article
- Oncologists' views on ototoxicity monitoring in head and neck cancer patients: A South Indian qualitative study.PloS one · 2025Article
- Unmet Needs and Care Delivery Gaps Among Rural Cancer Survivors.Journal of patient experience · 2024Article
- Practice of Monitoring Cisplatin-Induced Ototoxicity by Audiology, ENT, and Oncology Specialists: A Survey-Based Study in a Single Italian Medical Center.Audiology research · 2023Article
- Hearing screening and amplifier uptake results in a multidisciplinary head and neck cancer survivorship clinic.Journal of cancer survivorship : research and practice · 2023Article
- Association of hearing loss and tinnitus symptoms with health-related quality of life among long-term oropharyngeal cancer survivors.Cancer medicine · 2023Article
- Cisplatin-associated ototoxicity: perspectives from a single institution cervical cancer cohort and implications for developing a locally responsive monitoring programme in a public healthcare setting.BMC health services research · 2022Article
- Incorporating Patient Narratives to Enhance Audiological Care and Clinical Research Outcomes.American journal of audiology · 2021Article
- Clinical Considerations for Routine Auditory and Vestibular Monitoring in Patients With Cystic Fibrosis.American journal of audiology · 2021Article
- Pharmacotherapy of Tinnitus.Current topics in behavioral neurosciences · 2021Review
- Ototoxicity prevention during the SARS-CoV-2 (COVID-19) emergency.Journal of global antimicrobial resistance · 2020Article
- Roadmap to a Global Template for Implementation of Ototoxicity Management for Cancer Treatment.Ear and hearingReview
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionOtotoxicity associated with platinum-based chemotherapy is highly prevalent and can cause detrimental consequences among cancer survivors. DISCUSSION: In this article, we highlight important aspects of the evaluation of ototoxicity with the aim to increase awareness of Oncologists in this regard. Standard pure tone audiometry alone is inadequate for this context. Comprehensive and consistent hearing tests should be implemented in a monitoring and surveillance program. High-frequency audiometry (10-16 kHz) is a sensitive tool in the detection of ototoxic hearing loss at onset. In addition to threshold audiometry, measures of speech comprehension (both in quiet and in noise) can add useful information in the evaluation of hearing in real-life situations. Not only hearing loss, but also tinnitus and imbalance are common in patients who receive platinum-based chemotherapy, and can cause debilitating effects upon quality of life in this population. Moreover, self-report measures associated with cochlear and vestibular handicaps can provide valuable information regarding the impact of ototoxicity.
conclusionsIt is vital to build awareness about the variety and impact of the symptoms of ototoxicity. Comprehensive evaluation of hearing status along with self-reported impact of the cochlear and vestibular handicap should be implemented in a monitoring and surveillance program for appropriate investigation and management.
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