Evidence map›Paper›PMID 31865407›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

Milan Grkovski, Zachary A Kohutek, Heiko Schöder, Cameron W Brennan, Viviane S Tabar, Philip H Gutin, Zhigang Zhang, Robert J Young, Bradley J Beattie, Pat B Zanzonico and 5 more

Open access · greenAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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  12. Editorial commentary to "European journal of nuclear medicine and molecular imaging · 2020
    Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Milan GrkovskiDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.ORCID 0000-0001-7228-9497
Zachary A KohutekDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Heiko SchöderDepartment of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Cameron W BrennanDepartment of Neurosurgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Viviane S TabarDepartment of Neurosurgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Philip H GutinDepartment of Neurosurgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Zhigang ZhangDepartment of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Robert J YoungDepartment of Radiation Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
Bradley J BeattieDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Pat B ZanzonicoDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Jason T HuseHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Marc K RosenblumDepartment of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Ronald G BlasbergDepartment of Radiation Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
John L HummDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Kathryn BealDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA. bealk@mskcc.org.
Memorial Sloan Kettering Cancer Center · USVanderbilt University Medical Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Imaging drug uptake and distribution in chemoradiation therapy of pancreatic cancerR01CA194321 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI HUMM, JOHN L, PILLARSETTY, NAGAVARAKISHORE · 2016 to 2019
$2.7M
18F-Fluorocholine to distinguish necrosis from recurrence in brain metastasesR21CA170289 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI BEAL, KATHRYN, BLASBERG, RONALD GEORGE · 2013 to 2014
$723k
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA194321NCI NIH HHS R21 CA170289
6 · The paper itself

Abstract

purposeRadiographic changes of brain metastases after stereotactic radiosurgery (SRS) can signify tumor recurrence and/or radiation necrosis (RN); however, standard imaging modalities cannot easily distinguish between these two entities. We investigated whether

methodsAbout 14 patients previously treated with SRS that developed radiographic changes were included. All patients underwent a preoperative 40-min dynamic PET/CT concurrent with 392 ± 11 MBq bolus injection of

resultsExactly 10 out of 12 patients for which surgical samples were acquired exhibited pathologic recurrence. Strong correlation was observed between SUV

conclusions

Indexed as

Brain NeoplasmsRadiosurgeryCholineHumansKineticsNeoplasm Recurrence, LocalPositron-Emission TomographyPositron Emission Tomography Computed TomographyCholinefluorocholine18F-FluorocholineBrain metastasisKinetic modelingNecrosisPathology

Identifiers

PMID31865407
PMCPMC7596690
OpenAlexW2996363321

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.