Evidence map›Paper›PMID 31865385›Full record

ArticleEndocrinology2020

Commentary on the Recent FSH Collection: Known Knowns and Known Unknowns.

Djurdjica Coss

Open access · bronzeAbstract read
In one paragraph

Article in Endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Bone-organ axes: bidirectional crosstalk.Military Medical Research · 2024
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Crosstalk of Brain and Bone-Clinical Observations and Their Molecular Bases.International journal of molecular sciences · 2020
    Review
  10. Article
  11. Article
  12. Tell Me Your Superpower!Endocrinology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Djurdjica CossDivision of Biomedical Sciences; School of Medicine, University of California, Riverside; Riverside, California.
University of California, Riverside · US

Funding

The Role of AP1 Family Members in Hormone Gene ExpressionR01HD091167 · NICHD · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI COSS, DJURDJICA · 2018 to 2022
$1.7M
NICHD NIH HHS R01 HD091167
6 · The paper itself

Abstract

Follicle-stimulating hormone (FSH) is a dimeric glycoprotein secreted by the anterior pituitary gonadotrope that is necessary for reproductive function in mammals. FSH primarily regulates granulosa cells and follicular growth in females, and Sertoli cell function in males. Since its identification in the 1930s and sequencing in the 1970s, significant progress has been made in elucidating its regulation and downstream function. Recent advances provide deeper insight into FSH synthesis, and effects in the gonads suggest potential roles in extragonadal tissues and examine pharmacological approaches and clinical applications in infertility treatment that now affect 18% of couples. These advances were discussed in detail in a number of reviews published in the last 2 years in Endocrinology. In this brief commentary, we summarize these reviews and point to the outstanding questions that should be answered in the near future to bridge a gap in our understanding of this hormone.

Indexed as

Gene Expression RegulationProtein Processing, Post-TranslationalAnimalsFemaleFollicle Stimulating HormoneGranulosa CellsHumansMaleOvarian FollicleProtein BindingProtein SubunitsReceptors, FSHReview Literature as TopicSertoli CellsSignal TransductionSpermatogenesisFollicle Stimulating HormoneProtein SubunitsReceptors, FSHFSHglycosylationgonadotropegranulosa cellsovarypituitarySertoli cells

Identifiers

PMID31865385
PMCPMC6986550
OpenAlexW2997050147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.