Evidence map›Paper›PMID 31865172›Full record

ArticleAddictive behaviors2020

The epidemiology of alcohol use disorders cross-nationally: Findings from the World Mental Health Surveys.

Meyer D Glantz, Chrianna Bharat, Louisa Degenhardt, Nancy A Sampson, Kate M Scott, Carmen C W Lim, Ali Al-Hamzawi, Jordi Alonso, Laura Helena Andrade, Graca Cardoso and 27 more

Erratum issued Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Addictive behaviors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06840652 (Safety and Efficacy Assessment of Baclofen for Alcohol Withdrawal in Patients With Chronic Liver Disease and Active Alcohol Consumption), which is not on this map. Cited by 142 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
142citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06840652 enrolling by invitationnot on this mapstarted 2022, after this paper: background citation

Safety and Efficacy Assessment of Baclofen for Alcohol Withdrawal in Patients With Chronic Liver Disease and Active Alcohol Consumption

Typeobservational_patient_registrySponsorCorporacion Parc TauliRan2022 to 2026Enrolled120ConditionsAlcoholic Cirrhosis, Alcohol Abstinence, Alcohol Withdrawal, Medication ToxicityArmsBaclofen
3 · Its place in the literature

Who cites it

142 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Baclofen for alcohol use disorder.The Cochrane database of systematic reviews · 2023
    Pooled it
  8. Pooled it
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Relapse in alcohol dependence is characterized by disrupted modular brain network organization.European archives of psychiatry and clinical neuroscience · 2026
    Article
  19. Article
  20. Article

82 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

37 authors.

Meyer D GlantzDivision of Epidemiology, Services, and Prevention Research (DESPR), National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), Bethesda, MD, USA. Electronic address: mglantz@nida.nih.gov.
Chrianna BharatNational Drug and Alcohol Research Centre (NDARC), UNSW, Sydney, Australia.
Louisa DegenhardtNational Drug and Alcohol Research Centre (NDARC), UNSW, Sydney, Australia.
Nancy A SampsonDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Kate M ScottDepartment of Psychological Medicine, University of Otago, Dunedin, Otago, New Zealand.
Carmen C W LimQueensland Centre for Mental Health Research and Queensland Brain Institute, The University of Queensland, St. Lucia, Queensland, Australia.
Ali Al-HamzawiCollege of Medicine, Al-Qadisiya University, Diwaniya governorate, Iraq.
Jordi AlonsoHealth Services Research Unit, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain; CIBER en Epidemiología y Salud Pública (CIBERESP), Spain; Pompeu Fabra University (UPF), Barcelona, Spain.
Laura Helena AndradeNúcleo de Epidemiologia Psiquiátrica - LIM 23, Instituto de Psiquiatria Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, Brazil.
Graca CardosoLisbon Institute of Global Mental Health and Chronic Diseases Research Center (CEDOC), NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.
Giovanni De GirolamoUnit of Epidemiological and Evaluation Psychiatry, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS)-St. John of God Clinical Research Centre, Brescia, Italy.
Oye GurejeFRCPsych, Department of Psychiatry, University College Hospital, Ibadan, Nigeria.
Yanling HeShanghai Mental Health Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
Hristo HinkovNational Center of Public Health and Analyses, Sofia, Bulgaria.
Elie G KaramDepartment of Psychiatry and Clinical Psychology, Faculty of Medicine, Balamand University, Beirut, Lebanon; Department of Psychiatry and Clinical Psychology, St George Hospital University Medical Center, Beirut, Lebanon; Institute for Development Research Advocacy and Applied Care (IDRAAC), Beirut, Lebanon.
Georges KaramDepartment of Psychiatry and Clinical Psychology, St George Hospital University Medical Center, Balamand University, Faculty of Medicine, Beirut, Lebanon; Institute for Development Research Advocacy and Applied Care (IDRAAC), Beirut, Lebanon.
Viviane Kovess-MasfetyEcole des Hautes Etudes en Santé Publique (EHESP), EA 4057, Paris Descartes University, Paris, France.
Victor LasebikanDepartment of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Sing LeeDepartment of Psychiatry, Chinese University of Hong Kong, Tai Po, Hong Kong.
Daphna LevinsonMental Health Services, Ministry of Health, Jerusalem, Israel.
John McGrathQueensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Queensland, Australia; Queensland Brain Institute, University of Queensland, St. Lucia, Queensland, Australia; National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.
Maria-Elena Medina-MoraNational Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, Mexico.
Constanta Mihaescu-PintiaNational School of Public Health, Management and Professional Development, Bucharest, Romania.
Zeina MneimnehSurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Jacek MoskalewiczInstitute of Psychiatry and Neurology, Warsaw, Poland.
Fernando Navarro-MateuUDIF-SM, Subdirección General de Planificación, Innovación y Cronicidad, Servicio Murciano de Salud, IMIB-Arrixaca, CIBERESP-Murcia, Murcia, Spain.
José Posada-VillaColegio Mayor de Cundinamarca University, Faculty of Social Sciences, Bogota, Colombia.
Charlene RapseyPGDipClinPsych, University of Otago, Dunedin School of Medicine, Department of Psychological Medicine, New Zealand.
Juan Carlos StagnaroDepartamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
Hisateru TachimoriNational Institute of Mental Health, National Center for Neurology and Psychiatry, Kodaira, Tokyo, Japan.
Margreet Ten HaveTrimbos-Instituut, Netherlands Institute of Mental Health and Addiction, Utrecht, the Netherlands.
Nathan TintleDepartment of Mathematics, Statistics and Computer Science, Dordt College, Sioux Center, Iowa, USA.
Yolanda TorresCenter for Excellence on Research in Mental Health, CES University, Medellin, Colombia.
David R WilliamsDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Yuval ZivMental Health Services, Israeli Ministry of Health, 39 Yermiyahu St, Jerusalem 9101002, Israel.
Ronald C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
WHO World Mental Health Survey Collaborators

Funding

EPIDEMIOLOGY-- NATIONAL COMORBIDITY SURVEY REPLICATIONU01MH060220 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 1999 to 2010
$18.7M
Risk Factors for Psychopathology in the WHO WMH SurveysR01MH070884 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2005 to 2009
$6.0M
Trauma, Stress, and Mental Health in South AfricaR01MH059575 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WILLIAMS, DAVID R · 1998 to 2007
$2.5M
Social Role Disability and Mental-Physical Co-MorbidityR01MH069864 · NIMH · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2004 to 2007
$2.2M
COMORBID MENTAL DISORDERS IN PERIODS OF SOCIAL DISRUPTIOR01MH061905 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI BROMET, EVELYN J · 2000 to 2004
$1.7M
CROSS-NATIONAL STUDIES OF DRUG INVOLVEMENT: WMH2000R01DA016558 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2008
$1.7M
World Mental Health Consortium Annual Meeting 2003-07R13MH066849 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEERINGA, STEVEN G · 2003 to 2007
$735k
Using existing data to understand and ameliorate risk in opioid agonist therapyR01DA044170 · NIDA · UNIVERSITY OF NEW SOUTH WALES · PI DEGENHARDT, LOUISA · 2017 to 2019
$641k
Lebanon-Epidemiology: The NCS Replication StudyR03TW006481 · FIC · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2004 to 2006
$142k
FIC NIH HHS R03 TW006481NIDA NIH HHS R01 DA016558NIDA NIH HHS R01 DA044170NIMH NIH HHS R01 MH059575NIMH NIH HHS R01 MH061905NIMH NIH HHS R01 MH069864NIMH NIH HHS R01 MH070884NIMH NIH HHS R13 MH066849NIMH NIH HHS U01 MH060220
6 · The paper itself

Abstract

backgroundPrevalences of Alcohol Use Disorders (AUDs) and Mental Health Disorders (MHDs) in many individual countries have been reported but there are few cross-national studies. The WHO World Mental Health (WMH) Survey Initiative standardizes methodological factors facilitating comparison of the prevalences and associated factors of AUDs in a large number of countries to identify differences and commonalities.

methodsLifetime and 12-month prevalence estimates of DSM-IV AUDs, MHDs, and associations were assessed in the 29 WMH surveys using the WHO CIDI 3.0.

resultsPrevalence estimates of alcohol use and AUD across countries and WHO regions varied widely. Mean lifetime prevalence of alcohol use in all countries combined was 80%, ranging from 3.8% to 97.1%. Combined average population lifetime and 12-month prevalence of AUDs were 8.6% and 2.2% respectively and 10.7% and 4.4% among non-abstainers. Of individuals with a lifetime AUD, 43.9% had at least one lifetime MHD and 17.9% of respondents with a lifetime MHD had a lifetime AUD. For most comorbidity combinations, the MHD preceded the onset of the AUD. AUD prevalence was much higher for men than women. 15% of all lifetime AUD cases developed before age 18. Higher household income and being older at time of interview, married, and more educated, were associated with a lower risk for lifetime AUD and AUD persistence.

conclusionsPrevalence of alcohol use and AUD is high overall, with large variation worldwide. The WMH surveys corroborate the wide geographic consistency of a number of well-documented clinical and epidemiological findings and patterns.

Indexed as

Population HealthAlcohol DrinkingAlcoholismComorbidityDiagnostic and Statistical Manual of Mental DisordersFemaleHealth SurveysHumansMaleMental DisordersPrevalenceWorld Health OrganizationAbuseAlcoholComorbidityDependencePrevalenceRemission

Identifiers

PMID31865172
PMCPMC7416527

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.