ArticleBMC veterinary research2019
Detection of rabies antibodies in wild boars in north-east Romania by a rabies ELISA test.
Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- A pseudovirus-based neutralizing antibody assay for measuring neutralizing antibody against rabies virus.Journal of clinical microbiology · 2026Article
- Integrated Surveillance ofAnimals : an open access journal from MDPI · 2026Article
- Without Borders? The Impact of Political Barriers and Land Use on the Animal Health Dynamics and Genetic Structures of Large Game Species in the Carpathian Basin and Surrounding Regions-A Systematic Review.Veterinary sciences · 2026Review
- Rabies Virus-Neutralizing Antibodies in Free-Ranging Invasive Wild Boars (Pathogens (Basel, Switzerland) · 2024Article
- Potency, immunogenicity, and efficacy of rabies vaccine: In vitro and in vivo approach.Immunity, inflammation and disease · 2024Article
- Whole genome sequencing and phylogenetic characterisation of rabies virus strains from Moldova and north-eastern Romania.PLoS neglected tropical diseases · 2023Article
- Detection of immunity in sheep following anti-rabies vaccination.Clinical and experimental vaccine research · 2023Article
- Filter Papers to Collect Blood Samples from Dogs: An Easier Way to Monitor the Mass Vaccination Campaigns against Rabies?Viruses · 2022Article
- Oral vaccination of foxes and raccoon dogs against rabies with the 3rd generation oral rabies virus vaccine, SPBN GASGAS, in Finland.Acta veterinaria Scandinavica · 2021Article
- Detection and quantification of anti-rabies glycoprotein antibodies: current state and perspectives.Applied microbiology and biotechnology · 2021Review
- One Health Paradigm to Confront Zoonotic Health Threats: A Pakistan Prospective.Frontiers in microbiology · 2021Review
- The Presence of Rabies Virus-Neutralizing Antibody in Wild Boars (Veterinary sciences · 2020Article
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the last few decades, Romania has been considered one of the European countries most affected by animal rabies, but a combination of oral rabies vaccination (ORV) campaigns in foxes alongside mandatory vaccination of pets has substantially decreased the number of rabies cases in recent years. The objective of this study was to detect rabies antibodies in wild boar serum and thoracic fluid samples collected during the hunting season after ORV campaigns in north-eastern Romania in order to identify if wild boars are substantial competitors to foxes for ORV baits.
resultsWhen the 312 wild boar samples were tested by ELISA (BioPro ELISA, Czech Republic), 42.31% (132/312) demonstrated rabies antibodies. In order to compare these wild boar results in terms of the percentage of immunisation, fox samples were also included in the study, and in this case only 28.40% (98/345) demonstrated rabies antibodies by ELISA. To check the diagnostic sensitivity and specificity of this ELISA, those samples with a sufficient volume from both species that had tested either negative or positive with an initial ELISA were then tested with the Fluorescent Antibody Virus Neutralisation (FAVN) assay. The overall concordance between the BioPro ELISA and FAVN test was 74.26% (75/101) in wild boar samples and 65.66% (65/99) in fox samples, 140 out of 200 samples being correlated with the two methods, although no significant statistical difference (p = 0.218) between the two species was registered. We found a good agreement by both tests for the ELISA-positive samples (91.30%), however the situation was different for the ELISA-negative samples, where a low agreement was demonstrated (41.18%).
conclusionsThis study reports for the first time the presence of rabies antibodies in wild boar samples collected during the hunting season in Romania after ORV campaigns in rabies endemic areas. It is also the first study to demonstrate that ELISA BioPro can be used on wild boar samples with satisfactory results compared to the FAVN test for this species.
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