Evidence map›Paper›PMID 31864289›Full record

ArticleBMC cardiovascular disorders2019

Influence of heart rate control on exercise capacity and quality of life in patients with permanent atrial fibrillation.

Fei She, Yuan Ma, Yi Li, Lei Li, Weixian Xu, Hongyan Wang, Ming Cui

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Fei SheDepartment of Cardiology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Yuan MaDepartment of Cardiology, Peking University Third Hospital, 49 North garden Road, Haidian District, Beijing, China.
Yi LiDepartment of Cardiology, Peking University Third Hospital, 49 North garden Road, Haidian District, Beijing, China.
Lei LiDepartment of Cardiology, Peking University Third Hospital, 49 North garden Road, Haidian District, Beijing, China.
Weixian XuDepartment of Cardiology, Peking University Third Hospital, 49 North garden Road, Haidian District, Beijing, China.
Hongyan WangDepartment of Cardiology, Peking University Third Hospital, 49 North garden Road, Haidian District, Beijing, China.
Ming CuiDepartment of Cardiology, Peking University Third Hospital, 49 North garden Road, Haidian District, Beijing, China. cuiming70@163.com.ORCID 0000-0002-5185-2751
Ministry of Education of the People's Republic of China · CNBeijing Tsinghua Chang Gung Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal level of heart rate (HR) control in patients with atrial fibrillation (AF) is unknown. To assess the effect of rate control on cardiopulmonary exercise capacity and quality of life (QoL) in permanent AF.

methodsOne hundred forty-three patients with permanent AF were enrolled in this study. All patients received rate control medications and were followed up for 1 year. After 1-year therapy, the exercise capacity and QoL were evaluated by cardiopulmonary exercise testing (CPET) and 36-item Short-Form Health Survey, respectively. Data were compared by dividing the patients according to the following criteria: (1) whether the resting HR was ≤80 or > 80 bpm; (2) whether the exercise HR during moderate exercises on CPET was ≤110 or > 110 bpm; and (3) whether the resting HR was ≤80 bpm and exercise HR was ≤110 bpm.

resultsNo significant differences in peak oxygen uptake, peak metabolic equivalent, and anaerobic threshold were found between the strict control and lenient control groups. Both physical component summary (PCS) and mental component summary (MCS) were significantly higher for the strict rate control group than for the lenient control group. The single-factor correlation analysis revealed a negative correlation between resting HR and both PCS and MCS. The multivariable linear regression analysis indicated that both exercise HR and duration of AF linearly correlated with PCS and MCS.

conclusionsTherefore, in patients with permanent AF, exercise capacity may not be affected by the stringency of rate control, and strict rate control may be associated with better QoL.

Indexed as

Cardiorespiratory FitnessExercise ToleranceQuality of LifeAgedAnti-Arrhythmia AgentsAtrial FibrillationFemaleHeart RateHumansMaleProspective StudiesTime FactorsTreatment OutcomeAnti-Arrhythmia AgentsAnaerobic thresholdHeart rate controlPeak metabolic equivalentPeak oxygen uptakePermanent atrial fibrillationQuality of life

Identifiers

PMID31864289
PMCPMC6925461
OpenAlexW2995792089

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.