ArticleEnvironment international2020
Diesel exhaust and bladder cancer risk by pathologic stage and grade subtypes.
Article in Environment international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Occupational-Related Exposure to Diesel Exhaust and Kidney Cancer: Systematic Review and Meta-Analysis of Cohort Studies.La Medicina del lavoro · 2025Pooled it
- Global, regional, and national burdens of bladder cancer in individuals aged 60 years and older from 1990 to 2021: a cross-sectional study.International urology and nephrology · 2026Article
- Overview of tumor-resident intratumoral microbiota in human bladder cancer.Translational andrology and urology · 2026Article
- Article
- Airborne particulate matter and diesel engine exhaust on infrastructure construction sites in the Copenhagen metropolitan area.Annals of work exposures and health · 2024Article
- Landscape analysis of environmental data sources for linkage with SEER cancer patients database.Journal of the National Cancer Institute. Monographs · 2024Article
- Risk Factors Associated with Urothelial Bladder Cancer.International journal of environmental research and public health · 2024Review
- Nomograms for predicting the overall and cancer-specific survival in patients with non-urothelial carcinoma of the bladder: A population-based study.Biomolecules & biomedicine · 2024Article
- Occupational exposures of firefighting and urinary tract cancer risk among men in the Norwegian Fire Departments Cohort.Occupational and environmental medicine · 2023Article
- Diesel Exhaust Exposure and Cause-Specific Mortality in the Diesel Exhaust in Miners Study II (DEMS II) Cohort.Environmental health perspectives · 2023Article
- Nitrated Polycyclic Aromatic Hydrocarbon (Nitro-PAH) Signatures and Somatic Mutations in Diesel Exhaust-Exposed Bladder Tumors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Article
- How Does Environmental and Occupational Exposure Contribute to Carcinogenesis in Genitourinary and Lung Cancers?Cancers · 2023Review
- Long-term ambient hydrocarbon exposure and incidence of urinary bladder cancer.Scientific reports · 2022Article
- Occupational Mortality Matrix: A Tool for Epidemiological Assessment of Work-Related Risk Based on Current Data Sources.International journal of environmental research and public health · 2022Article
- Proteomic analysis of serum in workers exposed to diesel engine exhaust.Environmental and molecular mutagenesis · 2022Article
- Elevated urinary mutagenicity among those exposed to bituminous coal combustion emissions or diesel engine exhaust.Environmental and molecular mutagenesis · 2021Article
- The need for, and challenges associated with, assessing occupational work histories for bladder and other occupational cancers.Occupational and environmental medicine · 2021Article
- Road traffic and air pollution: Evidence from a nationwide traffic control during coronavirus disease 2019 outbreak.The Science of the total environment · 2021Article
- Targeted Deep Sequencing of Bladder Tumors Reveals Novel Associations between Cancer Gene Mutations and Mutational Signatures with Major Risk Factors.Clinical cancer research : an official journal of the American Association for Cancer Research · 2021Article
- Diesel Exhaust Exposure during Farming Activities: Statistical Modeling of Continuous Black Carbon Concentrations.Annals of work exposures and health · 2020Article
Corrections and comments
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Authors and funding
26 authors at 13 institutions in 3 countries.
Funding
Abstract
backgroundThe International Agency for Research on Cancer (IARC) classifies diesel engine exhaust as carcinogenic to humans based on sufficient evidence for lung cancer. IARC noted, however, an increased risk of bladder cancer (based on limited evidence).
objectiveTo evaluate the association between quantitative, lifetime occupational diesel exhaust exposure and risk of urothelial cell carcinoma of the bladder (UBC) overall and according to pathological subtypes.
methodsData from personal interviews with 1944 UBC cases, as well as formalin-fixed paraffin-embedded tumor tissue blocks, and 2135 controls were pooled from two case-control studies conducted in the U.S. and Spain. Lifetime occupational histories combined with exposure-oriented questions were used to estimate cumulative exposure to respirable elemental carbon (REC), a primary surrogate for diesel exhaust. Unconditional logistic regression and two-stage polytomous logistic regression were used to calculate odds ratios (ORs) and 95% confidence intervals (CIs), adjusting for smoking and other risk factors.
resultsExposure to cumulative REC was associated with an increased risk of UBC; workers with cumulative REC >396 μg/m
conclusionsCombining data from two large epidemiologic studies, our results provide further evidence that diesel exhaust exposure increases the risk of UBC.
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Registered trials
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