ArticleCNS neuroscience & therapeutics2020
Dentate nNOS accounts for stress-induced 5-HT
Article in CNS neuroscience & therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 13 citations in OpenAlex.
- Targeting the 5-HTCell & bioscience · 2026Article
- Oxygen-dependent regulation of serotonin receptoriScience · 2025Article
- Ameliorative Effect of Moringa oleifera Against CUMS-Induced Anxiety in Rats: β-Catenin and 5-HTMolecular neurobiology · 2025Article
- Longitudinal non-negative matrix factorization identifies the altered trajectory of motor symptoms in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Restoration of nNOS Expression Rescues Autistic-Like Phenotypes Through Normalization of AMPA Receptor-Mediated Neurotransmission.Molecular neurobiology · 2024Article
- Mitigation of behavioral deficits and cognitive impairment by antioxidant and neuromodulatory potential ofSaudi journal of biological sciences · 2023Article
- Requirement of hippocampal DG nNOS-CAPON dissociation for the anxiolytic and antidepressant effects of fluoxetine.Theranostics · 2022Article
- D-galactose induced dysfunction in mice hippocampus and the possible antioxidant and neuromodulatory effects of selenium.Environmental science and pollution research international · 2022Article
- Modulation of the Serotonergic Receptosome in the Treatment of Anxiety and Depression: A Narrative Review of the Experimental Evidence.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Dentate nNOS accounts for stress-induced 5-HTCNS neuroscience & therapeutics · 2020Article
- Identification of New Targets and the Virtual Screening of Lignans against Alzheimer's Disease.Oxidative medicine and cellular longevity · 2020Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnxiety is a common disorder with high social burden worldwide. Dysfunction of serotonin-
methodsUsing pharmacological and genetic methods, we investigated the role of detate nNOS in 5-HT
resultsHere we showed that local elevation of glucocorticoids in the DG accounted for chronic stress-induced anxiety behavior. Neuronal nitric oxide synthase (nNOS) mediated chronic stress-induced downregulation of 5-HT
conclusionsThese findings uncovered an important role of nNOS-5-HT
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.