Evidence map›Paper›PMID 31863647›Full record

ArticleBirth defects research2020

Pre-pregnancy dietary arsenic consumption among women in the United States.

Jonathan Suhl, Kristin M Conway, Anthony Rhoads, Peter H Langlois, Marcia L Feldkamp, Adrian Michalski, Paul A Romitti, National Birth Defects Prevention Study

Abstract read
In one paragraph

Article in Birth defects research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Arsenic and Obesity: a Review of Causation and Interaction.Current environmental health reports · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jonathan SuhlDepartment of Epidemiology, College of Public Health, The University of Iowa, Iowa City, Iowa.
Kristin M ConwayDepartment of Epidemiology, College of Public Health, The University of Iowa, Iowa City, Iowa.
Anthony RhoadsDepartment of Epidemiology, College of Public Health, The University of Iowa, Iowa City, Iowa.
Peter H LangloisBirth Defects Epidemiology and Surveillance Branch, Texas Department of State Health Services, Austin, Texas.ORCID 0000-0001-6765-4963
Marcia L FeldkampDivision of Medical Genetics, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.ORCID 0000-0001-9171-7848
Adrian MichalskiNew York State Department of Health, Bureau of Environmental and Occupational Epidemiology, Albany, New York.
Paul A RomittiDepartment of Epidemiology, College of Public Health, The University of Iowa, Iowa City, Iowa.ORCID 0000-0001-5393-9984
National Birth Defects Prevention Study

Funding

The Heartland Center for Occupational Health and Safety Education and Research CenterT42OH008491 · OH · UNIVERSITY OF IOWA · PI O'SHAUGHNESSY, PATRICK T · 2005 to 2025
$31.7M
Iowa CBDRP: Component A BD-STEPS II CoreU01DD001223 · DD · UNIVERSITY OF IOWA · PI CONWAY, KRISTIN, ROMITTI, PAUL A · 2018 to 2022
$4.3M
New York State Component A: BD-STEPS II CoreU01DD001227 · DD · CENTER OF ENVIRONMENTAL HEALTH · PI HOWLEY, MEREDITH M · 2018 to 2022
$4.2M
Iowa CBDRP: Birth Defects Study To Evaluate Pregnancy exposureSU01DD001035 · DD · UNIVERSITY OF IOWA · PI ROMITTI, PAUL A · 2013 to 2017
$3.5M
EPA EP-D-18-001HSRD VA CDP 13-003NCBDD CDC HHS U01 DD001035NCBDD CDC HHS U01 DD001223NCBDD CDC HHS U01 DD001227NIOSH CDC HHS T42 OH008491
6 · The paper itself

Abstract

backgroundArsenic is associated with several adverse health outcomes, including some birth defects. Although diet is the predominant route of arsenic exposure in the United States (U.S.), limited data exist regarding pre-pregnancy dietary arsenic consumption among U.S. women.

methodsUsing data collected in the National Birth Defects Prevention Study (NBDPS), we estimated daily dietary arsenic consumption during the year before pregnancy for 10,886 mothers of nonmalformed control children delivered from 1997-2011. Responses to the NBDPS dietary assessment and food item estimates of total and inorganic arsenic were used to estimate consumption. Associations between total and inorganic arsenic consumption and selected maternal characteristics were estimated using multinomial logistic regression.

resultsEstimates of mean maternal total and inorganic dietary arsenic consumption were 14.9 and 5.2 μg/day, respectively. Several positive and inverse associations with confidence intervals that excluded the null were observed. Comparing mothers in the middle or high total arsenic consumption tertiles to those in the low tertile, we observed positive associations (odds ratios = 1.3-3.8) for maternal age (≥30 years), lower (0-8 years) or higher (>12 years) education, race/ethnicity (non-Hispanic Black, Hispanic, other), and early pregnancy drinking with no binge episodes, and inverse associations (odds ratios = 0.4-0.8) for age (<25 years), body mass index (≥30.0 kg/m

conclusionsThese contemporary estimates of pre-pregnancy dietary arsenic consumption among U.S. women show associations between both total and inorganic dietary arsenic consumption and several maternal characteristics, improving characterization of the public health impact of this exposure.

Indexed as

ArsenicChildDietFemaleHumansLogistic ModelsMaternal AgeOdds RatioPregnancyUnited StatesArsenicarsenicbirth defectsdietpopulation-basedpregnancy

Identifiers

PMID31863647
PMCPMC7099603

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.