Evidence map›Paper›PMID 31863400›Full record

ArticleJournal of neurovirology2020

Diagnosing acute encephalitis in patients with hematological disorders: caveats and pitfalls.

Elisa Vegezzi, Giulia Berzero, Desiree Barbetta, Anna Amelia Colombo, Oscar Borsani, Paolo Bernasconi, Francesca Compagno, Marco Zecca, Giulia Campanini, Anna Simoncelli and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurovirology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Elisa VegezziNeuroncology Unit, IRCCS Mondino Foundation, Pavia, Italy.
Giulia BerzeroNeuroncology Unit, IRCCS Mondino Foundation, Pavia, Italy.
Desiree BarbettaInfectious and Tropical Diseases Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Anna Amelia ColomboBone Marrow Transplantation Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Oscar BorsaniBone Marrow Transplantation Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Paolo BernasconiBone Marrow Transplantation Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Francesca CompagnoPediatric Hematology/Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Marco ZeccaPediatric Hematology/Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Giulia CampaniniMolecular Virology Unit, Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Anna SimoncelliDiagnostic Radiology, Interventional Radiology and Neuroradiology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Matteo PaolettiNeuroradiology Unit, IRCCS Mondino Foundation, Pavia, Italy.
Anna PichiecchioDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Fausto BaldantiMolecular Virology Unit, Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Enrico BrunettiInfectious and Tropical Diseases Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Enrico MarchioniNeuroncology Unit, IRCCS Mondino Foundation, Pavia, Italy. enrico.marchioni@mondino.it.
University of Pavia · ITPoliclinico San Matteo Fondazione · ITFondazione Istituto Neurologico Nazionale Casimiro Mondino · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to review the quality of the diagnostic work-up for acute encephalitis carried out at our center in a cohort of patients with hematological disorders. Our data showed substantial heterogeneity in investigating patients. Not all patients had their CSF tested for viruses commonly responsible for encephalitis in immunocompetent individuals (e.g., VZV, enterovirus). A blood sample for the calculation of the CSF/blood replication ratio was collected in 74% of cases. CSF cultures and immunophenotyping of CSF cells were performed in 77% and 21% of patients, respectively. A multidisciplinary consensus is needed to improve current guidelines and standardize diagnostic protocols.

Indexed as

AdolescentAdultAgedChildEncephalitisFemaleHematologic DiseasesHumansMaleMiddle AgedRetrospective StudiesYoung AdultAcute encephalitisDiagnosisHematological disordersHematopoietic stem cell transplantationImmunocompromised patients

Identifiers

PMID31863400
OpenAlexW2995000054

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.