Evidence map›Paper›PMID 31863371›Full record

ArticleEnvironmental science and pollution research international2020

Senna alexandrina extract supplementation reverses hepatic oxidative, inflammatory, and apoptotic effects of cadmium chloride administration in rats.

Xianbin Wang, Ting Wang, Tingting Pan, Mei Huang, Weihua Ren, Geliang Xu, Hatem K Amin, Rami B Kassab, Ahmed E Abdel Moneim

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Curative Potential of Substances with Bioactive Properties to Alleviate Cd Toxicity: A Review.International journal of environmental research and public health · 2022
    Review
  7. Article
  8. Selenium-containing polysaccharide fromFrontiers in nutrition · 2022
    Article
  9. Article
  10. Article
  11. Exposure to arsenite and cadmium induces organotoxicity and miRNAs deregulation in male rats.Environmental science and pollution research international · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Xianbin WangDepartment of Graduate School, Tianjin Medical University, Tianjin, 300051, China.
Ting WangDepartment of Radiology, The Second Affiliated Hospital of Baotou Medical College, Baotou, 014030, Neimenggu, China.
Tingting PanDepartment of General Surgery, The First Affiliated Hospital of USTC, Hefei, 230001, Anhui, China.
Mei HuangDepartment of General Surgery, The First Affiliated Hospital of USTC, Hefei, 230001, Anhui, China.
Weihua RenDepartment of General Surgery, The First Affiliated Hospital of USTC, Hefei, 230001, Anhui, China.
Geliang XuDepartment of General Surgery, The First Affiliated Hospital of USTC, Hefei, 230001, Anhui, China. xugeliang2019@sina.com.
Hatem K AminDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
Rami B KassabDepartment of Zoology and Entomology, Faculty of Science, Helwan University, Cairo, Egypt.
Ahmed E Abdel MoneimDepartment of Zoology and Entomology, Faculty of Science, Helwan University, Cairo, Egypt.
Helwan University · EGBaotou Medical College · CNTianjin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Senna alexandrina is traditionally used for its antioxidant and anti-inflammatory properties, but little information is available concerning its potential protective effects against cadmium, which is a widespread environmental toxicant that causes hepatotoxicity. Here, we explored the effects of S. alexandrina extract (SAE) on cadmium chloride (CdCl

Indexed as

Senna PlantAnimalsAntioxidantsApoptosisCadmiumCadmium ChlorideDietary SupplementsHazardous SubstancesLiverOxidative StressProtective AgentsRatsSenna ExtractSennosidesSuperoxide DismutaseAntioxidantsCadmiumCadmium ChlorideHazardous SubstancesProtective AgentsSenna ExtractSennosidesSuperoxide DismutaseApoptosisCadmiumInflammationLiverNuclear factor erythroid 2-related factor 2Oxidative stressSenna alexandrina

Identifiers

PMID31863371
OpenAlexW2995444994

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.