Evidence map›Paper›PMID 31863307›Full record

ArticleWorld journal of microbiology & biotechnology2019

Aggregation, adhesion and efficacy studies of probiotic candidate Pediococcus acidilactici NCDC 252: a strain of dairy origin.

Raman Kumar, Poonam Bansal, Jasbir Singh, Suman Dhanda, Jitender Kumar Bhardwaj

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Foods (Basel, Switzerland) · 2026
    Article
  2. Article
  3. ProbioticFoods (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Pharmaceutics · 2023
    Article
  7. Antidiabetic Effects ofNutrients · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Raman KumarDepartment of Biochemistry, Kurukshetra University Kurukshetra, Kurukshetra, Haryana, 136119, India.
Poonam BansalDepartment of Biochemistry, Kurukshetra University Kurukshetra, Kurukshetra, Haryana, 136119, India.
Jasbir SinghDepartment of Biochemistry, Kurukshetra University Kurukshetra, Kurukshetra, Haryana, 136119, India.
Suman DhandaDepartment of Biochemistry, Kurukshetra University Kurukshetra, Kurukshetra, Haryana, 136119, India. dhanda.suman999@gmail.com.ORCID http://orcid.org/0000-0002-4707-1207
Jitender Kumar BhardwajDepartment of Zoology, Kurukshetra University Kurukshetra, Kurukshetra, India.
Kurukshetra University · IN

Funding

Department of Science and Technology, New Delhi, India NO. SB/YS/LS-180/2014
6 · The paper itself

Abstract

Aggregation and adhesion capability and survival efficacy of candidate probiotic strain Pediococcus acidilactici NCDC 252 under simulated gastric, intestinal and vaginal conditions was studied. The strain exhibited strong autoaggregation phenotype and coaggregation with other Lactic acid bacteria (LAB) and E. coli. The adhesion studies of NCDC 252 to pig's intestinal epithelial cells showed its adhesive ability. Aggregation and adhesiveness were related through cell surface proteins as removal/extraction of surface proteins resulted in altered aggregation and no adhesiveness. Cell surface proteins were analysed by SDS-PAGE and also in silico analysed from its genome. SDS-PAGE analysis of cell surface proteins of NCDC 252 revealed two potential proteins of approximately 74.3 and 53.6 kDa to be involved in host-probiotic interaction. Removal of cell surface proteins by LiCl-treatment (5 mol l

Indexed as

AnimalsBacterial AdhesionDietary SupplementsEpithelial CellsFemaleGastrointestinal TractHumansLactobacillalesMembrane ProteinsMicrobial ViabilityMolecular Docking SimulationMucinsPediococcus acidilacticiProbioticsVaginaMembrane ProteinsMucinsAggregationCell surface proteinsNCDC 252ProbioticsSimulated conditions

Identifiers

PMID31863307
OpenAlexW2995829914

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.