Evidence map›Paper›PMID 31863268›Full record

SynthesisJournal of behavioral medicine2020

The relationship between minority stress and biological outcomes: A systematic review.

Annesa Flentje, Nicholas C Heck, James Michael Brennan, Ilan H Meyer

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Journal of behavioral medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 176 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
176citing papers in PubMed, 10 pooled it
27.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

176 citing papers in PubMed, 10 syntheses or guidelines pooled it, 347 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Trial
  12. Differential gene expression in response to AWARENESS: A randomized controlled trial of an intersectional minority stress intervention.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Trial
  13. Article
  14. Identity among adolescent and young adult cancer survivors: an exploratory qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  15. Discrimination and Disordered Eating in Economically Disadvantaged Adults: A Multilevel, Longitudinal Study.Clinical psychological science : a journal of the Association for Psychological Science · 2026
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

116 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Annesa FlentjeCommunity Health Systems, School of Nursing, University of California, San Francisco, San Francisco, CA, USA. annesa.flentje@ucsf.edu.ORCID 0000-0002-1964-4151
Nicholas C HeckPutnam County Hospital, Greencastle, IN, USA.
James Michael BrennanDepartment of Psychology, The University of Montana, Missoula, MT, USA.
Ilan H MeyerThe Williams Institute, School of Law, University of California, Los Angeles, Los Angeles, CA, USA.
University of California, Los Angeles · USUniversity of California, San Francisco · USUniversity of Montana · US

Funding

Scientific and Technical CoreP2CHD041022 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HIRAM BELTRAN-SANCHEZ · 2016 to 2026
$6.9M
Identity Stress and Health in Three Cohorts of LGB individualsR01HD078526 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MEYER, ILAN H · 2014 to 2018
$4.1M
Gene expression outcomes in interventions for substance using HIV+ minority menK23DA039800 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FLENTJE, ANNESA · 2015 to 2019
$1.0M
NICHD NIH HHS P2C HD041022NICHD NIH HHS R01 HD078526NIDA NIH HHS K23 DA039800
6 · The paper itself

Abstract

Sexual minority (non-heterosexual) individuals experience higher rates of physical health problems. Minority stress has been the primary explanatory model to account for this disparity. The purpose of this study was to identify in published research empirically established relationships between minority stress processes and biological outcomes and identify avenues for future research. The PubMed database was queried with search terms relevant to minority stress and a comprehensive list of physical and biological outcomes. To be included in the analysis, studies had to examine the relationship between minority stress and a biological outcome among sexual minority individuals. Those meeting inclusion criteria were coded for key variables including methodology used, positive and null results, participant characteristics, and specific minority stress processes and biological outcomes considered. In total, 26 studies met inclusion criteria. Studies tested relationships between specific minority stress processes including prejudice, expectations of prejudice, concealment of sexual orientation, and internalized stigma and multiple biological outcomes, such as overall physical health, immune response, HIV specific outcomes, cardiovascular outcomes, metabolic outcomes, cancer related outcomes, and hormonal outcomes. Studies included both analyses that detected this relationship (42% of analyses) and analyses that did not detect this relationship (58%). There is substantial evidence to support the relationship between minority stress and biological outcomes, yet additional research is needed to identify the measurements and outcomes that have the most rigorous and replicable results.

Indexed as

BisexualitySexual and Gender MinoritiesFemaleHumansMaleMinority GroupsSexual BehaviorSocial StigmaStress, PsychologicalBiological outcomesBisexualGayLesbianMinority stressSexual minority

Identifiers

PMID31863268
PMCPMC7430236
OpenAlexW2996460582

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.